Genomic RNA folding mediates assembly of human parechovirus
The mechanism underlying packaging of genomic RNA into viral particles is not well understood for human parechoviruses. Here the authors identify short RNA motifs in the parechovirus genome that bind capsid proteins, providing approximately 60 specific interactions for virion assembly.
Main Authors: | Shabih Shakeel, Eric C. Dykeman, Simon J. White, Ari Ora, Joseph J.B. Cockburn, Sarah J. Butcher, Peter G. Stockley, Reidun Twarock |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-016-0011-z |
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