Research prioritization of men’s health and urologic diseases
ABSTRACT Objectives We sought to determine whether disease representation in the Cochrane Database of Systematic Reviews (CDSR) reflects disease burden, measured by the Global Burden of Disease (GBD) Study as disability-adjusted life-years (DALYs). Materials and Methods Two investigators perform...
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doaj-1ee7eaec636845c7a0c72058b123a4282020-11-25T00:30:36ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-611943228930310.1590/s1677-5538.ibju.2016.0047S1677-55382017000200289Research prioritization of men’s health and urologic diseasesTyler OklandChante KarimkhaniHannah PedersonLindsay N. BoyersMark D. SawyerKyle O. RoveMcCabe C. KennySteven SteinbergMohsen NaghaviRobert P. DellavalleABSTRACT Objectives We sought to determine whether disease representation in the Cochrane Database of Systematic Reviews (CDSR) reflects disease burden, measured by the Global Burden of Disease (GBD) Study as disability-adjusted life-years (DALYs). Materials and Methods Two investigators performed independent assessment of ten men’s health and urologic diseases (MHUDs) in CDSR for systematic review and protocol representation, which were compared with percentage of total 2010 DALYs for the ten conditions. Data were analyzed for correlation using Spearman rank analysis. Results Nine of ten MHUDs were represented by at least one CDSR review. There was a poor and statistically insignificant positive correlation between CDSR representation and disease burden (rho = 0.42, p = 0.23). CDSR representation was aligned with disease burden for three conditions, greater than disease burden for one condition, and less than disease burden for six conditions. Conclusions These results yield high-quality estimates to inform future research prioritization for MHUDs. While prioritization processes are complex and multi-faceted, disease burden should be strongly considered. Awareness of research priority setting has the potential to minimize research disparities on a global scale.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382017000200289&lng=en&tlng=enMen’s HealthUrologic DiseasesNeoplasmsInfertility, Male |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Tyler Okland Chante Karimkhani Hannah Pederson Lindsay N. Boyers Mark D. Sawyer Kyle O. Rove McCabe C. Kenny Steven Steinberg Mohsen Naghavi Robert P. Dellavalle |
spellingShingle |
Tyler Okland Chante Karimkhani Hannah Pederson Lindsay N. Boyers Mark D. Sawyer Kyle O. Rove McCabe C. Kenny Steven Steinberg Mohsen Naghavi Robert P. Dellavalle Research prioritization of men’s health and urologic diseases International Brazilian Journal of Urology Men’s Health Urologic Diseases Neoplasms Infertility, Male |
author_facet |
Tyler Okland Chante Karimkhani Hannah Pederson Lindsay N. Boyers Mark D. Sawyer Kyle O. Rove McCabe C. Kenny Steven Steinberg Mohsen Naghavi Robert P. Dellavalle |
author_sort |
Tyler Okland |
title |
Research prioritization of men’s health and urologic diseases |
title_short |
Research prioritization of men’s health and urologic diseases |
title_full |
Research prioritization of men’s health and urologic diseases |
title_fullStr |
Research prioritization of men’s health and urologic diseases |
title_full_unstemmed |
Research prioritization of men’s health and urologic diseases |
title_sort |
research prioritization of men’s health and urologic diseases |
publisher |
Sociedade Brasileira de Urologia |
series |
International Brazilian Journal of Urology |
issn |
1677-6119 |
description |
ABSTRACT Objectives We sought to determine whether disease representation in the Cochrane Database of Systematic Reviews (CDSR) reflects disease burden, measured by the Global Burden of Disease (GBD) Study as disability-adjusted life-years (DALYs). Materials and Methods Two investigators performed independent assessment of ten men’s health and urologic diseases (MHUDs) in CDSR for systematic review and protocol representation, which were compared with percentage of total 2010 DALYs for the ten conditions. Data were analyzed for correlation using Spearman rank analysis. Results Nine of ten MHUDs were represented by at least one CDSR review. There was a poor and statistically insignificant positive correlation between CDSR representation and disease burden (rho = 0.42, p = 0.23). CDSR representation was aligned with disease burden for three conditions, greater than disease burden for one condition, and less than disease burden for six conditions. Conclusions These results yield high-quality estimates to inform future research prioritization for MHUDs. While prioritization processes are complex and multi-faceted, disease burden should be strongly considered. Awareness of research priority setting has the potential to minimize research disparities on a global scale. |
topic |
Men’s Health Urologic Diseases Neoplasms Infertility, Male |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382017000200289&lng=en&tlng=en |
work_keys_str_mv |
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1725325911819026432 |