Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis

Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis

Epstein–Barr virus (EBV) is a ubiquitous virus that infects nearly all people worldwide without serious sequela. However, for patients who have genetic diseases which predispose them to the development of hemophagocytic lymphohistiocytosis (HLH), EBV infection is a life-threatening problem. As a par...

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Main Author: Rebecca A. Marsh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Epstein–Barr virus
hemophagocytic lymphohistiocytosis
primary immunodeficiency
X-linked Lymphoproliferative Disease
Mononucleosis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01902/full
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spelling doaj-1ef5e89913e04ad49423882b6b193b1c2020-11-24T22:32:31ZengFrontiers Media S.A.Frontiers in Immunology1664-32242018-01-01810.3389/fimmu.2017.01902317920Epstein–Barr Virus and Hemophagocytic LymphohistiocytosisRebecca A. Marsh0Division of Bone Marrow Transplantation and Immune Deficiency, Cancer and Blood Diseases Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United StatesEpstein–Barr virus (EBV) is a ubiquitous virus that infects nearly all people worldwide without serious sequela. However, for patients who have genetic diseases which predispose them to the development of hemophagocytic lymphohistiocytosis (HLH), EBV infection is a life-threatening problem. As a part of a themed collection of articles on EBV infection and human primary immune deficiencies, we will review key concepts related to the understanding and treatment of HLH.http://journal.frontiersin.org/article/10.3389/fimmu.2017.01902/fullEpstein–Barr virushemophagocytic lymphohistiocytosisprimary immunodeficiencyX-linked Lymphoproliferative DiseaseMononucleosis
collection DOAJ
language English
format Article
sources DOAJ
author Rebecca A. Marsh
spellingShingle Rebecca A. Marsh
Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
Frontiers in Immunology
Epstein–Barr virus
hemophagocytic lymphohistiocytosis
primary immunodeficiency
X-linked Lymphoproliferative Disease
Mononucleosis
author_facet Rebecca A. Marsh
author_sort Rebecca A. Marsh
title Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title_short Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title_full Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title_fullStr Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title_full_unstemmed Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis
title_sort epstein–barr virus and hemophagocytic lymphohistiocytosis
publisher Frontiers Media S.A.
series Frontiers in Immunology
issn 1664-3224
publishDate 2018-01-01
description Epstein–Barr virus (EBV) is a ubiquitous virus that infects nearly all people worldwide without serious sequela. However, for patients who have genetic diseases which predispose them to the development of hemophagocytic lymphohistiocytosis (HLH), EBV infection is a life-threatening problem. As a part of a themed collection of articles on EBV infection and human primary immune deficiencies, we will review key concepts related to the understanding and treatment of HLH.
topic Epstein–Barr virus
hemophagocytic lymphohistiocytosis
primary immunodeficiency
X-linked Lymphoproliferative Disease
Mononucleosis
url http://journal.frontiersin.org/article/10.3389/fimmu.2017.01902/full
work_keys_str_mv AT rebeccaamarsh epsteinbarrvirusandhemophagocyticlymphohistiocytosis
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