A quantitative MRI method for imaging blood-brain barrier leakage in experimental traumatic brain injury.

Blood-brain barrier (BBB) disruption is common following traumatic brain injury (TBI). Dynamic contrast enhanced (DCE) MRI can longitudinally measure the transport coefficient Ktrans which reflects BBB permeability. Ktrans measurements however are not widely used in TBI research because it is genera...

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Bibliographic Details
Main Authors: Wei Li, Justin Alexander Long, Lora Talley Watts, Zhao Jiang, Qiang Shen, Yunxia Li, Timothy Q Duong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4257611?pdf=render