COX-2 Gene Promoter Polymorphism and Coronary Artery Disease in Middle-Aged Men: The Helsinki Sudden Death Study
Cyclooxygenase (COX) catalyzes formation of prostaglandins that contribute to the inflammation in atherosclerosis. Our objective was to study whether the functional C variant of the −765G→C polymorphism in the human COX-2 gene associates with the severity of coronary atherosclerosis measured at the...
Main Authors: | Kati H. Huuskonen, Tarja A. Kunnas, Minna M. Tanner, Jussi Mikkelsson, Erkki Ilveskoski, Pekka J. Karhunen, Seppo T. Nikkari |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2008-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2008/289453 |
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