Three-Dimensional Regeneration of Patient-Derived Intestinal Organoid Epithelium in a Physiodynamic Mucosal Interface-on-a-Chip

Three-Dimensional Regeneration of Patient-Derived Intestinal Organoid Epithelium in a Physiodynamic Mucosal Interface-on-a-Chip

The regeneration of the mucosal interface of the human intestine is critical in the host–gut microbiome crosstalk associated with gastrointestinal diseases. The biopsy-derived intestinal organoids provide genetic information of patients with physiological cytodifferentiation. However, the enclosed l...

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Bibliographic Details
Main Authors: Yong Cheol Shin, Woojung Shin, Domin Koh, Alexander Wu, Yoko M. Ambrosini, Soyoun Min, S. Gail Eckhardt, R. Y. Declan Fleming, Seung Kim, Sowon Park, Hong Koh, Tae Kyung Yoo, Hyun Jung Kim
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Micromachines
Subjects:
gut-on-a-chip
organoid
mucosal interface
physiodynamic
multiaxial deformation
microbiome
Online Access:https://www.mdpi.com/2072-666X/11/7/663

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