Structural basis for dolichylphosphate mannose biosynthesis
The generation of glycolipid dolichylphosphate mannose (Dol-P-Man) is a critical step for protein glycosylation and GPI anchor synthesis. Here the authors report the structure of dolichylphosphate mannose synthase in complex with bound nucleotide and donor to provide insight into the mechanism of Do...
Main Authors: | Rosaria Gandini, Tom Reichenbach, Tien-Chye Tan, Christina Divne |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-00187-2 |
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