Notch2 and Notch3 function together to regulate vascular smooth muscle development.
Notch signaling has been implicated in the regulation of smooth muscle differentiation, but the precise role of Notch receptors is ill defined. Although Notch3 receptor expression is high in smooth muscle, Notch3 mutant mice are viable and display only mild defects in vascular patterning and smooth...
Main Authors: | Qingqing Wang, Ning Zhao, Simone Kennard, Brenda Lilly |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3355134?pdf=render |
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