Feasibility of urinary extracellular vesicle proteome profiling using a robust and simple, clinically applicable isolation method

Feasibility of urinary extracellular vesicle proteome profiling using a robust and simple, clinically applicable isolation method

Extracellular vesicles (EVs) secreted by prostate cancer (PCa) cells contain specific biomarkers and can be isolated from urine. Collection of urine is not invasive, and therefore urinary EVs represent a liquid biopsy for diagnostic and prognostic testing for PCa. In this study, we optimised urinary...

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Bibliographic Details
Main Authors: Irene V. Bijnsdorp, Olga Maxouri, Aarzo Kardar, Tim Schelfhorst, Sander R. Piersma, Thang V. Pham, Andre Vis, R. Jeroen van Moorselaar, Connie R. Jimenez
Format: Article
Language:English
Published: Taylor & Francis Group 2017-12-01
Series:Journal of Extracellular Vesicles
Subjects:
Extracellular vesicles
exosome isolation
urinary EVs
proteomics
METM-kit
prostate cancer
Online Access:http://dx.doi.org/10.1080/20013078.2017.1313091

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