Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas.

Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas.

The human Matrix MetalloProtease-9 (hMMP-9) is overexpressed in tumors where it promotes the release of cancer cells thus contributing to tumor metastasis. We raised aptamers against hMMP-9, which constitutes a validated marker of malignant tumors, in order to design probes for imaging tumors in hum...

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Bibliographic Details
Main Authors: David Kryza, Frédéric Debordeaux, Laurent Azéma, Aref Hassan, Olivier Paurelle, Jürgen Schulz, Catherine Savona-Baron, Elsa Charignon, Pauline Bonazza, Jacqueline Taleb, Philippe Fernandez, Marc Janier, Jean Jacques Toulmé
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4762761?pdf=render

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http://europepmc.org/articles/PMC4762761?pdf=render

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