Synthesis of some Heterocyclic Compounds Derived from 2-Chloro-N-p-Tolylacetamide

Synthesis of some Heterocyclic Compounds Derived from 2-Chloro-N-p-Tolylacetamide

This research includes preparation of (2-chloro-N-p-tolylacetamide) (1) from the reaction of (p-aminotoluene) with chloro acetyl chloride. Compound (1) reacted with thiosemi carbazide and gave compound (2), and when compound (1) reacted with semicarbazide gave compound (3). While when compound (1) r...

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Bibliographic Details
Main Author: Hanan Gh Shaaban
Format: Article
Language:Arabic
Published: Al-Mustansiriyah University 2017-02-01
Series:Mustansiriyah Journal of Science
Subjects:
Hetroylic, p-aminotoluene, aromaticaldehydes,Sshiff bass, β-lactam
Online Access:http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/26
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spelling doaj-1f643adcf9f8404c9162c25cc6d4aa962020-11-24T20:53:33ZaraAl-Mustansiriyah UniversityMustansiriyah Journal of Science1814-635X2521-35202017-02-0127410.23851/mjs.v27i4.2623Synthesis of some Heterocyclic Compounds Derived from 2-Chloro-N-p-TolylacetamideHanan Gh Shaaban0Department of Chemistry, College of Science, Al-Mustansiriyah University, Iraq.This research includes preparation of (2-chloro-N-p-tolylacetamide) (1) from the reaction of (p-aminotoluene) with chloro acetyl chloride. Compound (1) reacted with thiosemi carbazide and gave compound (2), and when compound (1) reacted with semicarbazide gave compound (3). While when compound (1) reacted with thiourea it produced compound (4). Compounds (2-4) when reacted with appropriate aromatic aldehydes or ketones produced Shiff bass (5-16), which in turn reacted with chloro acetyl chloride in the present of tri ethyl amine and dioxin gave β-lactam derivatives (14-22). The structures of these compounds were characterized from their melting points, FT-IR, and NMR.http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/26Hetroylic, p-aminotoluene, aromaticaldehydes,Sshiff bass, β-lactam
collection DOAJ
language Arabic
format Article
sources DOAJ
author Hanan Gh Shaaban
spellingShingle Hanan Gh Shaaban
Synthesis of some Heterocyclic Compounds Derived from 2-Chloro-N-p-Tolylacetamide
Mustansiriyah Journal of Science
Hetroylic, p-aminotoluene, aromaticaldehydes,Sshiff bass, β-lactam
author_facet Hanan Gh Shaaban
author_sort Hanan Gh Shaaban
title Synthesis of some Heterocyclic Compounds Derived from 2-Chloro-N-p-Tolylacetamide
title_short Synthesis of some Heterocyclic Compounds Derived from 2-Chloro-N-p-Tolylacetamide
title_full Synthesis of some Heterocyclic Compounds Derived from 2-Chloro-N-p-Tolylacetamide
title_fullStr Synthesis of some Heterocyclic Compounds Derived from 2-Chloro-N-p-Tolylacetamide
title_full_unstemmed Synthesis of some Heterocyclic Compounds Derived from 2-Chloro-N-p-Tolylacetamide
title_sort synthesis of some heterocyclic compounds derived from 2-chloro-n-p-tolylacetamide
publisher Al-Mustansiriyah University
series Mustansiriyah Journal of Science
issn 1814-635X
2521-3520
publishDate 2017-02-01
description This research includes preparation of (2-chloro-N-p-tolylacetamide) (1) from the reaction of (p-aminotoluene) with chloro acetyl chloride. Compound (1) reacted with thiosemi carbazide and gave compound (2), and when compound (1) reacted with semicarbazide gave compound (3). While when compound (1) reacted with thiourea it produced compound (4). Compounds (2-4) when reacted with appropriate aromatic aldehydes or ketones produced Shiff bass (5-16), which in turn reacted with chloro acetyl chloride in the present of tri ethyl amine and dioxin gave β-lactam derivatives (14-22). The structures of these compounds were characterized from their melting points, FT-IR, and NMR.
topic Hetroylic, p-aminotoluene, aromaticaldehydes,Sshiff bass, β-lactam
url http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/26
work_keys_str_mv AT hananghshaaban synthesisofsomeheterocycliccompoundsderivedfrom2chloronptolylacetamide
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