Screening analysis of retinopathy for prematurity in Shantou

• Main Authors: Gui-Hua Zhang, Wei-Qi Chen, Hao-Yu Chen, Kun Peng, Du-Sheng Lin
• Format: Article
• Language: English
• Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-08-01
• Series: Guoji Yanke Zazhi
• Subjects: retinopathy; prematurity/epidemiology; prematurity/etiology; prematurity/diagnosis; neonatal screening
• Online Access: http://ies.ijo.cn/cn_publish/2015/8/201508041.pdf

AIM:To determine the incidence of retinopathy of prematurity(ROP)and to investigate the appropriate criteria for the screening ROP in Shantou. <p>METHODS: A total of 1 813 infants with birth weight ≤2 000g or gestational age ≤34wk in neonatal intensive care units(NICU)of four hospitals in Shantou were screened with binocular indirect ophthalmoscope and(or)wild-field digital pediatric retinal imaging system(RetCamⅡ )from January 2011 to December 2014. All infants were followed up until the retina was completely vascularized or until the disease regressed.<p>RESULTS:In all infants, ROP was detected in 388 eyes of 202 cases(11.14%), including 85 eyes of 43 cases(2.37%)suffering from severe ROP(threshold or pre-threshold type Ⅰ ROP). 34 severe cases(67 eyes)were screened out in 408 infants with birth weight <1 500g, accounted for 79.07% in all severe cases. GEE model analysis indicated that low birth weight, small gestational age and oxygen therapy were high risk factors of ROP. <p>CONCLUSION:The detection rate of ROP is 11.14% in Shantou NICU. However, the detection rate of severe ROP is lower, mainly in the infants with birth weight <1 500g and gestational age ≤34wk; Low birth weight, small gestational age and oxygen therapy are high risk factors of ROP.