Indicator Regularized Non-Negative Matrix Factorization Method-Based Drug Repurposing for COVID-19
A novel coronavirus, named COVID-19, has become one of the most prevalent and severe infectious diseases in human history. Currently, there are only very few vaccines and therapeutic drugs against COVID-19, and their efficacies are yet to be tested. Drug repurposing aims to explore new applications...
Main Authors: | Xianfang Tang, Lijun Cai, Yajie Meng, JunLin Xu, Changcheng Lu, Jialiang Yang |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-01-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2020.603615/full |
Similar Items
-
Drug repurposing with network reinforcement
by: Yonghyun Nam, et al.
Published: (2019-07-01) -
Repurposing of a muscle relaxant drug thiocolchicoside as an anticancer agent
by: Shreya Medhi, et al.
Published: (2021-01-01) -
Semi-Supervised Community Detection via Constraint Matrix Construction and Active Node Selection
by: Suqi Zhang, et al.
Published: (2020-01-01) -
Drug Repurposing for Triple-Negative Breast Cancer
by: Marta Ávalos-Moreno, et al.
Published: (2020-10-01) -
Discriminative and Graph Regularized Nonnegative Matrix Factorization with Kernel Method
by: LI Xiangli, ZHANG Ying
Published: (2020-11-01)