Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment?
Addiction management is complex, and it requires a bio-psycho-social perspective, that ought to consider the multiple etiological and developmental factors. Because of this, a large amount of resources has been allocated to assess the vulnerability to dependence, i.e., to identify the processes unde...
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Frontiers Media S.A.
2020-07-01
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Series: | Frontiers in Psychiatry |
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Online Access: | https://www.frontiersin.org/article/10.3389/fpsyt.2020.00676/full |
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record_format |
Article |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rosa Jurado-Barba Rosa Jurado-Barba Ana Sion Ana Sion Andrés Martínez-Maldonado Isabel Domínguez-Centeno Julio Prieto-Montalvo Francisco Navarrete Francisco Navarrete María Salud García-Gutierrez María Salud García-Gutierrez Jorge Manzanares Jorge Manzanares Gabriel Rubio Gabriel Rubio Gabriel Rubio |
spellingShingle |
Rosa Jurado-Barba Rosa Jurado-Barba Ana Sion Ana Sion Andrés Martínez-Maldonado Isabel Domínguez-Centeno Julio Prieto-Montalvo Francisco Navarrete Francisco Navarrete María Salud García-Gutierrez María Salud García-Gutierrez Jorge Manzanares Jorge Manzanares Gabriel Rubio Gabriel Rubio Gabriel Rubio Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment? Frontiers in Psychiatry alcohol dependence electroencephalogram endophenotypes incentive salience negative emotionality executive dimension |
author_facet |
Rosa Jurado-Barba Rosa Jurado-Barba Ana Sion Ana Sion Andrés Martínez-Maldonado Isabel Domínguez-Centeno Julio Prieto-Montalvo Francisco Navarrete Francisco Navarrete María Salud García-Gutierrez María Salud García-Gutierrez Jorge Manzanares Jorge Manzanares Gabriel Rubio Gabriel Rubio Gabriel Rubio |
author_sort |
Rosa Jurado-Barba |
title |
Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment? |
title_short |
Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment? |
title_full |
Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment? |
title_fullStr |
Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment? |
title_full_unstemmed |
Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment? |
title_sort |
neuropsychophysiological measures of alcohol dependence: can we use eeg in the clinical assessment? |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Psychiatry |
issn |
1664-0640 |
publishDate |
2020-07-01 |
description |
Addiction management is complex, and it requires a bio-psycho-social perspective, that ought to consider the multiple etiological and developmental factors. Because of this, a large amount of resources has been allocated to assess the vulnerability to dependence, i.e., to identify the processes underlying the transition from substance use to dependence, as well as its course, in order to determine the key points in its prevention, treatment, and recovery. Consequently, knowledge \from neuroscience must be taken into account, which is why different initiatives have emerged with this objective, such as the “Research Domain Criteria” (RDoC), and the “Addiction Neuroclinical Assessment” (ANA). Particularly, neuropsychophysiological measures could be used as markers of cognitive and behavioral attributes or traits in alcohol dependence, and even trace clinical change. In this way, the aim of this narrative review is to provide an overview following ANA clinical framework, to the most robust findings in neuropsychophysiological changes in alcohol dependence, that underlie the main cognitive domains implicated in addiction: incentive salience, negative emotionality, and executive functioning. The most consistent results have been found in event-related potential (ERP) analysis, especially in the P3 component, that could show a wide clinical utility, mainly for the executive functions. The review also shows the usefulness of other components, implicated in affective and substance-related processing (P1, N1, or the late positive potential LPP), as well as event-related oscillations, such as theta power, with a possible use as vulnerability or clinical marker in alcohol dependence. Finally, new tools emerging from psychophysiology research, based on functional connectivity or brain graph analysis could help toward a better understanding of altered circuits in alcohol dependence, as well as communication efficiency and effort during mental operations. This review concludes with an examination of these tools as possible markers in the clinical field and discusses methodological differences, the need for more replicability studies and incipient lines of work. It also uses consistent findings in psychophysiology to draw possible treatment targets and cognitive profiles in alcohol dependence. |
topic |
alcohol dependence electroencephalogram endophenotypes incentive salience negative emotionality executive dimension |
url |
https://www.frontiersin.org/article/10.3389/fpsyt.2020.00676/full |
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doaj-1f6778983d994d8698899996ab2bac552020-11-25T02:33:47ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402020-07-011110.3389/fpsyt.2020.00676523188Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment?Rosa Jurado-Barba0Rosa Jurado-Barba1Ana Sion2Ana Sion3Andrés Martínez-Maldonado4Isabel Domínguez-Centeno5Julio Prieto-Montalvo6Francisco Navarrete7Francisco Navarrete8María Salud García-Gutierrez9María Salud García-Gutierrez10Jorge Manzanares11Jorge Manzanares12Gabriel Rubio13Gabriel Rubio14Gabriel Rubio15Biomedical Research Institute, Hospital 12 de Octubre, Madrid, SpainDepartment of Psychology, Education and Health Science Faculty, Camilo José Cela University, Madrid, SpainBiomedical Research Institute, Hospital 12 de Octubre, Madrid, SpainAddictive Disorders Network, Carlos III Institute, Madrid, SpainBiomedical Research Institute, Hospital 12 de Octubre, Madrid, SpainDepartment of Psychology, Education and Health Science Faculty, Camilo José Cela University, Madrid, SpainDepartment of Clinical Neurophysiology, Hospital Gregorio Marañón, Madrid, SpainAddictive Disorders Network, Carlos III Institute, Madrid, SpainNeuroscience Institute, Miguel Hernández University-CSIC, Alicante, SpainAddictive Disorders Network, Carlos III Institute, Madrid, SpainNeuroscience Institute, Miguel Hernández University-CSIC, Alicante, SpainAddictive Disorders Network, Carlos III Institute, Madrid, SpainNeuroscience Institute, Miguel Hernández University-CSIC, Alicante, SpainBiomedical Research Institute, Hospital 12 de Octubre, Madrid, SpainAddictive Disorders Network, Carlos III Institute, Madrid, SpainMedicine Faculty, Complutense de Madrid University, Madrid, SpainAddiction management is complex, and it requires a bio-psycho-social perspective, that ought to consider the multiple etiological and developmental factors. Because of this, a large amount of resources has been allocated to assess the vulnerability to dependence, i.e., to identify the processes underlying the transition from substance use to dependence, as well as its course, in order to determine the key points in its prevention, treatment, and recovery. Consequently, knowledge \from neuroscience must be taken into account, which is why different initiatives have emerged with this objective, such as the “Research Domain Criteria” (RDoC), and the “Addiction Neuroclinical Assessment” (ANA). Particularly, neuropsychophysiological measures could be used as markers of cognitive and behavioral attributes or traits in alcohol dependence, and even trace clinical change. In this way, the aim of this narrative review is to provide an overview following ANA clinical framework, to the most robust findings in neuropsychophysiological changes in alcohol dependence, that underlie the main cognitive domains implicated in addiction: incentive salience, negative emotionality, and executive functioning. The most consistent results have been found in event-related potential (ERP) analysis, especially in the P3 component, that could show a wide clinical utility, mainly for the executive functions. The review also shows the usefulness of other components, implicated in affective and substance-related processing (P1, N1, or the late positive potential LPP), as well as event-related oscillations, such as theta power, with a possible use as vulnerability or clinical marker in alcohol dependence. Finally, new tools emerging from psychophysiology research, based on functional connectivity or brain graph analysis could help toward a better understanding of altered circuits in alcohol dependence, as well as communication efficiency and effort during mental operations. This review concludes with an examination of these tools as possible markers in the clinical field and discusses methodological differences, the need for more replicability studies and incipient lines of work. It also uses consistent findings in psychophysiology to draw possible treatment targets and cognitive profiles in alcohol dependence.https://www.frontiersin.org/article/10.3389/fpsyt.2020.00676/fullalcohol dependenceelectroencephalogramendophenotypesincentive saliencenegative emotionalityexecutive dimension |