Giant parathyroid adenoma: a case report and review of the literature
Abstract Background Giant parathyroid adenoma is a rare type of parathyroid adenoma defined as weighing > 3.5 g. They present as primary hyperparathyroidism but with more elevated laboratory findings and more severe clinical presentations due to the larger tissue mass. This is the first reported...
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doaj-1fa68e66d2f845be9ec16acb620bd4d12020-11-25T04:09:54ZengBMCJournal of Medical Case Reports1752-19472019-11-011311910.1186/s13256-019-2257-7Giant parathyroid adenoma: a case report and review of the literatureMohamed S. Al-Hassan0Menatalla Mekhaimar1Walid El Ansari2Adham Darweesh3Abdelrahman Abdelaal4Department of General Surgery, Hamad General Hospital, Hamad Medical CorporationWeill Cornell Medicine-QatarDepartment of Surgery, Hamad General Hospital, Hamad Medical CorporationDepartment of Medical Imaging, Hamad General Hospital, Hamad Medical CorporationDepartment of General Surgery, Hamad General Hospital, Hamad Medical CorporationAbstract Background Giant parathyroid adenoma is a rare type of parathyroid adenoma defined as weighing > 3.5 g. They present as primary hyperparathyroidism but with more elevated laboratory findings and more severe clinical presentations due to the larger tissue mass. This is the first reported case of giant parathyroid adenoma from the Middle East. Case presentation A 52-year-old Indian woman presented with a palpable right-sided neck mass and generalized fatigue. Investigations revealed hypercalcemia with elevated parathyroid hormone and an asymptomatic kidney stone. Ultrasound showed a complex nodule with solid and cystic components, and Sestamibi nuclear scan confirmed a giant parathyroid adenoma. Focused surgical neck exploration was done and a giant parathyroid adenoma weighing 7.7 gm was excised. Conclusions Giant parathyroid adenoma is a rare cause of primary hyperparathyroidism and usually presents symptomatically with high calcium and parathyroid hormone levels. Giant parathyroid adenoma is diagnosed by imaging and laboratory studies. Management is typically surgical, aiming at complete resection. Patients usually recover with no long-term complications or recurrence.http://link.springer.com/article/10.1186/s13256-019-2257-7Giant parathyroid adenomaParathyroidectomyPrimary hyperparathyroidismMinimal invasive parathyroidectomyAtypical parathyroid adenoma |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohamed S. Al-Hassan Menatalla Mekhaimar Walid El Ansari Adham Darweesh Abdelrahman Abdelaal |
spellingShingle |
Mohamed S. Al-Hassan Menatalla Mekhaimar Walid El Ansari Adham Darweesh Abdelrahman Abdelaal Giant parathyroid adenoma: a case report and review of the literature Journal of Medical Case Reports Giant parathyroid adenoma Parathyroidectomy Primary hyperparathyroidism Minimal invasive parathyroidectomy Atypical parathyroid adenoma |
author_facet |
Mohamed S. Al-Hassan Menatalla Mekhaimar Walid El Ansari Adham Darweesh Abdelrahman Abdelaal |
author_sort |
Mohamed S. Al-Hassan |
title |
Giant parathyroid adenoma: a case report and review of the literature |
title_short |
Giant parathyroid adenoma: a case report and review of the literature |
title_full |
Giant parathyroid adenoma: a case report and review of the literature |
title_fullStr |
Giant parathyroid adenoma: a case report and review of the literature |
title_full_unstemmed |
Giant parathyroid adenoma: a case report and review of the literature |
title_sort |
giant parathyroid adenoma: a case report and review of the literature |
publisher |
BMC |
series |
Journal of Medical Case Reports |
issn |
1752-1947 |
publishDate |
2019-11-01 |
description |
Abstract Background Giant parathyroid adenoma is a rare type of parathyroid adenoma defined as weighing > 3.5 g. They present as primary hyperparathyroidism but with more elevated laboratory findings and more severe clinical presentations due to the larger tissue mass. This is the first reported case of giant parathyroid adenoma from the Middle East. Case presentation A 52-year-old Indian woman presented with a palpable right-sided neck mass and generalized fatigue. Investigations revealed hypercalcemia with elevated parathyroid hormone and an asymptomatic kidney stone. Ultrasound showed a complex nodule with solid and cystic components, and Sestamibi nuclear scan confirmed a giant parathyroid adenoma. Focused surgical neck exploration was done and a giant parathyroid adenoma weighing 7.7 gm was excised. Conclusions Giant parathyroid adenoma is a rare cause of primary hyperparathyroidism and usually presents symptomatically with high calcium and parathyroid hormone levels. Giant parathyroid adenoma is diagnosed by imaging and laboratory studies. Management is typically surgical, aiming at complete resection. Patients usually recover with no long-term complications or recurrence. |
topic |
Giant parathyroid adenoma Parathyroidectomy Primary hyperparathyroidism Minimal invasive parathyroidectomy Atypical parathyroid adenoma |
url |
http://link.springer.com/article/10.1186/s13256-019-2257-7 |
work_keys_str_mv |
AT mohamedsalhassan giantparathyroidadenomaacasereportandreviewoftheliterature AT menatallamekhaimar giantparathyroidadenomaacasereportandreviewoftheliterature AT walidelansari giantparathyroidadenomaacasereportandreviewoftheliterature AT adhamdarweesh giantparathyroidadenomaacasereportandreviewoftheliterature AT abdelrahmanabdelaal giantparathyroidadenomaacasereportandreviewoftheliterature |
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