Mast cell distribution around the needle tract following acupuncture in Zusanli (ST36) acupoint in rats
The aim of this study was to investigate mast cell (MCs) distribution in the vicinity of the needle tract formed after acupuncture in Zusanli (ST36) acupoint in rats. MCs were detected by histochemistry, immunohistochemistry and transmission electron microscopy, and evaluated quantitatively. It was...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria
2019-03-01
|
Series: | Bulgarian Journal of Veterinary Medicine |
Subjects: | |
Online Access: | http://tru.uni-sz.bg/bjvm/BJVM-March%202019%20p.91-98.pdf |
id |
doaj-1fbd00bf2a1e4e20a037c0d511527851 |
---|---|
record_format |
Article |
spelling |
doaj-1fbd00bf2a1e4e20a037c0d5115278512020-11-24T21:02:27ZengFaculty of Veterinary Medicine, Trakia University, Stara Zagora, BulgariaBulgarian Journal of Veterinary Medicine1311-14771313-35432019-03-01221919810.15547/bjvm.2066Mast cell distribution around the needle tract following acupuncture in Zusanli (ST36) acupoint in ratsN. D. Dimitrov0D. Y. Atanasova1N. S. Tomov2Y. A. Staykova-Pirovska3I. G. Ivanova 4D. P. Sivrev5Faculty of Medicine, Trakia University, Stara Zagora, BulgariaInstitute of Neurobiology, Bulgarian Academy of Sciences, Sofia, BulgariaFaculty of Medicine, Trakia University, Stara Zagora, BulgariaFaculty of Medicine, Trakia University, Stara Zagora, BulgariaFaculty of Medicine, Trakia University, Stara Zagora, BulgariaFaculty of Medicine, Trakia University, Stara Zagora, BulgariaThe aim of this study was to investigate mast cell (MCs) distribution in the vicinity of the needle tract formed after acupuncture in Zusanli (ST36) acupoint in rats. MCs were detected by histochemistry, immunohistochemistry and transmission electron microscopy, and evaluated quantitatively. It was established that after acupuncture in ST36 acupoint the integrity of the epithelium, dermis, subcutane-ous connective tissue, fascia, epimysium and striated muscles was disrupted and folded to the direc-tion of the needle tract. In the thickened connective tissue MCs were observed close to the needle tract, without visible differences in their number along the tract, but most of them were with signs of degranulation, possibly due to acupuncture. It could be presumed that acupuncture in ST36 caused recruitment and activation of MCs followed by degranulation which most probably influenced the local microenvironment.http://tru.uni-sz.bg/bjvm/BJVM-March%202019%20p.91-98.pdfacupuncturedegranulationmast cellsneedle tractZusanli (ST36) |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
N. D. Dimitrov D. Y. Atanasova N. S. Tomov Y. A. Staykova-Pirovska I. G. Ivanova D. P. Sivrev |
spellingShingle |
N. D. Dimitrov D. Y. Atanasova N. S. Tomov Y. A. Staykova-Pirovska I. G. Ivanova D. P. Sivrev Mast cell distribution around the needle tract following acupuncture in Zusanli (ST36) acupoint in rats Bulgarian Journal of Veterinary Medicine acupuncture degranulation mast cells needle tract Zusanli (ST36) |
author_facet |
N. D. Dimitrov D. Y. Atanasova N. S. Tomov Y. A. Staykova-Pirovska I. G. Ivanova D. P. Sivrev |
author_sort |
N. D. Dimitrov |
title |
Mast cell distribution around the needle tract following acupuncture in Zusanli (ST36) acupoint in rats |
title_short |
Mast cell distribution around the needle tract following acupuncture in Zusanli (ST36) acupoint in rats |
title_full |
Mast cell distribution around the needle tract following acupuncture in Zusanli (ST36) acupoint in rats |
title_fullStr |
Mast cell distribution around the needle tract following acupuncture in Zusanli (ST36) acupoint in rats |
title_full_unstemmed |
Mast cell distribution around the needle tract following acupuncture in Zusanli (ST36) acupoint in rats |
title_sort |
mast cell distribution around the needle tract following acupuncture in zusanli (st36) acupoint in rats |
publisher |
Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria |
series |
Bulgarian Journal of Veterinary Medicine |
issn |
1311-1477 1313-3543 |
publishDate |
2019-03-01 |
description |
The aim of this study was to investigate mast cell (MCs) distribution in the vicinity of the needle tract formed after acupuncture in Zusanli (ST36) acupoint in rats. MCs were detected by histochemistry, immunohistochemistry and transmission electron microscopy, and evaluated quantitatively. It was established that after acupuncture in ST36 acupoint the integrity of the epithelium, dermis, subcutane-ous connective tissue, fascia, epimysium and striated muscles was disrupted and folded to the direc-tion of the needle tract. In the thickened connective tissue MCs were observed close to the needle tract, without visible differences in their number along the tract, but most of them were with signs of degranulation, possibly due to acupuncture. It could be presumed that acupuncture in ST36 caused recruitment and activation of MCs followed by degranulation which most probably influenced the local microenvironment. |
topic |
acupuncture degranulation mast cells needle tract Zusanli (ST36) |
url |
http://tru.uni-sz.bg/bjvm/BJVM-March%202019%20p.91-98.pdf |
work_keys_str_mv |
AT nddimitrov mastcelldistributionaroundtheneedletractfollowingacupunctureinzusanlist36acupointinrats AT dyatanasova mastcelldistributionaroundtheneedletractfollowingacupunctureinzusanlist36acupointinrats AT nstomov mastcelldistributionaroundtheneedletractfollowingacupunctureinzusanlist36acupointinrats AT yastaykovapirovska mastcelldistributionaroundtheneedletractfollowingacupunctureinzusanlist36acupointinrats AT igivanova mastcelldistributionaroundtheneedletractfollowingacupunctureinzusanlist36acupointinrats AT dpsivrev mastcelldistributionaroundtheneedletractfollowingacupunctureinzusanlist36acupointinrats |
_version_ |
1716775344591077376 |