Suppressor of cytokine signaling 2 (Socs2) deletion protects bone health of mice with DSS-induced inflammatory bowel disease

Suppressor of cytokine signaling 2 (Socs2) deletion protects bone health of mice with DSS-induced inflammatory bowel disease

Individuals with inflammatory bowel disease (IBD) often present with poor bone health. The development of targeted therapies for this bone loss requires a fuller understanding of the underlying cellular mechanisms. Although bone loss in IBD is multifactorial, the altered sensitivity and secretion of...

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Bibliographic Details
Main Authors: Ross Dobie, Vicky E. MacRae, Chloe Pass, Elspeth M. Milne, S. Faisal Ahmed, Colin Farquharson
Format: Article
Language:English
Published: The Company of Biologists 2018-01-01
Series:Disease Models & Mechanisms
Subjects:
SOCS2
Inflammatory bowel disease
IBD
Growth hormone
Bone
Online Access:http://dmm.biologists.org/content/11/1/dmm028456

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