Nailfold videocapillaroscopy in antisynthetase syndrome
A 57-year-old woman with a diagnosis of antisynthetase syndrome (ASSD) underwent a nailfold videocapillaroscopy (NVC) showing a scleroderma pattern. Alterations in capillary morphology have been reported in adults with inflammatory myositis (IM) but only recently have the differences in NVC finding...
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doaj-1fcf68804ad04ab2bab9368220491e4d2020-11-24T22:52:54ZengPAGEPress PublicationsReumatismo0048-74492240-26832018-12-0170410.4081/reumatismo.2018.1105Nailfold videocapillaroscopy in antisynthetase syndromeG. Cassone0M. Sebastiani1L. Cavagna2K. Triantafyllias3V. Codullo4C. Salvarani5A. Manfredi6Rheumatology Unit, University of Modena and Reggio Emilia, ModenaRheumatology Unit, University of Modena and Reggio Emilia, ModenaDivision of Rheumatology, University and IRCCS Policlinico S. Matteo Foudation, PaviaACURA Rheumatology Clinics, Bad KreuznachDivision of Rheumatology, University and IRCCS Policlinico S. Matteo Foudation, PaviaRheumatology Unit, University of Modena and Reggio Emilia, ModenaRheumatology Unit, University of Modena and Reggio Emilia, Modena A 57-year-old woman with a diagnosis of antisynthetase syndrome (ASSD) underwent a nailfold videocapillaroscopy (NVC) showing a scleroderma pattern. Alterations in capillary morphology have been reported in adults with inflammatory myositis (IM) but only recently have the differences in NVC findings between these two diseases been established. ASSD is currently classified as a subset of IM, for which reason only a few studies in literature evaluate its specific hallmarks, showing nonspecific features of NVC in patients with polymyositis and dermatomyositis (DM) and antisynthetase antibodies. To our knowledge, this is the first description of ASSD capillaroscopy features, and the first report of NVC in ASSD with evidence of scleroderma pattern. Further studies are needed to define clearly frequency, typical features, and possible correlation with clinical and serological data of NVC changes in ASSD, differences between microangiopathy in ASSD and systemic sclerosis or DM. https://reumatismo.org/index.php/reuma/article/view/1105Nailfold videocapillaroscopyInflammatory myositisAntisynthetase syndromeRaynaud’s phenomenon. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
G. Cassone M. Sebastiani L. Cavagna K. Triantafyllias V. Codullo C. Salvarani A. Manfredi |
spellingShingle |
G. Cassone M. Sebastiani L. Cavagna K. Triantafyllias V. Codullo C. Salvarani A. Manfredi Nailfold videocapillaroscopy in antisynthetase syndrome Reumatismo Nailfold videocapillaroscopy Inflammatory myositis Antisynthetase syndrome Raynaud’s phenomenon. |
author_facet |
G. Cassone M. Sebastiani L. Cavagna K. Triantafyllias V. Codullo C. Salvarani A. Manfredi |
author_sort |
G. Cassone |
title |
Nailfold videocapillaroscopy in antisynthetase syndrome |
title_short |
Nailfold videocapillaroscopy in antisynthetase syndrome |
title_full |
Nailfold videocapillaroscopy in antisynthetase syndrome |
title_fullStr |
Nailfold videocapillaroscopy in antisynthetase syndrome |
title_full_unstemmed |
Nailfold videocapillaroscopy in antisynthetase syndrome |
title_sort |
nailfold videocapillaroscopy in antisynthetase syndrome |
publisher |
PAGEPress Publications |
series |
Reumatismo |
issn |
0048-7449 2240-2683 |
publishDate |
2018-12-01 |
description |
A 57-year-old woman with a diagnosis of antisynthetase syndrome (ASSD) underwent a nailfold videocapillaroscopy (NVC) showing a scleroderma pattern. Alterations in capillary morphology have been reported in adults with inflammatory myositis (IM) but only recently have the differences in NVC findings between these two diseases been established. ASSD is currently classified as a subset of IM, for which reason only a few studies in literature evaluate its specific hallmarks, showing nonspecific features of NVC in patients with polymyositis and dermatomyositis (DM) and antisynthetase antibodies. To our knowledge, this is the first description of ASSD capillaroscopy features, and the first report of NVC in ASSD with evidence of scleroderma pattern. Further studies are needed to define clearly frequency, typical features, and possible correlation with clinical and serological data of NVC changes in ASSD, differences between microangiopathy in ASSD and systemic sclerosis or DM.
|
topic |
Nailfold videocapillaroscopy Inflammatory myositis Antisynthetase syndrome Raynaud’s phenomenon. |
url |
https://reumatismo.org/index.php/reuma/article/view/1105 |
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