Successful mycophenolate mofetil treatment of a patient with severe steroid‐refractory hepatitis evoked by nivolumab plus ipilimumab treatment for relapsed bladder cancer

Successful mycophenolate mofetil treatment of a patient with severe steroid‐refractory hepatitis evoked by nivolumab plus ipilimumab treatment for relapsed bladder cancer

Abstract Mycophenolate mofetil resulted in rapid improvement of steroid‐refractory immune‐related adverse event hepatitis, induced by nivolumab plus ipilimumab.

Bibliographic Details
Main Authors: Ginji Omori, Kohichi Takada, Kazuyuki Murase, Naotaka Hayasaka, Hajime Nakamura, Satoshi Iyama, Hiroyuki Ohnuma, Koji Miyanishi, Fumimasa Fukuta, Toshiaki Tanaka, Naoya Masumori, Junji Kato
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Clinical Case Reports
Subjects:
hepatitis
immune‐related adverse events
ipilimumab
mycophenolate mofetil
nivolumab
Online Access:https://doi.org/10.1002/ccr3.3597
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spelling doaj-1feaba1a59b74169bd015a1233712e492021-02-08T11:42:41ZengWileyClinical Case Reports2050-09042021-02-019265465910.1002/ccr3.3597Successful mycophenolate mofetil treatment of a patient with severe steroid‐refractory hepatitis evoked by nivolumab plus ipilimumab treatment for relapsed bladder cancerGinji Omori0Kohichi Takada1Kazuyuki Murase2Naotaka Hayasaka3Hajime Nakamura4Satoshi Iyama5Hiroyuki Ohnuma6Koji Miyanishi7Fumimasa Fukuta8Toshiaki Tanaka9Naoya Masumori10Junji Kato11Department of Medical Oncology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Medical Oncology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Medical Oncology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Medical Oncology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Medical Oncology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Hematology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Medical Oncology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Medical Oncology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Urology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Urology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Urology Sapporo Medical University School of Medicine Sapporo JapanDepartment of Medical Oncology Sapporo Medical University School of Medicine Sapporo JapanAbstract Mycophenolate mofetil resulted in rapid improvement of steroid‐refractory immune‐related adverse event hepatitis, induced by nivolumab plus ipilimumab.https://doi.org/10.1002/ccr3.3597hepatitisimmune‐related adverse eventsipilimumabmycophenolate mofetilnivolumab
collection DOAJ
language English
format Article
sources DOAJ
author Ginji Omori
Kohichi Takada
Kazuyuki Murase
Naotaka Hayasaka
Hajime Nakamura
Satoshi Iyama
Hiroyuki Ohnuma
Koji Miyanishi
Fumimasa Fukuta
Toshiaki Tanaka
Naoya Masumori
Junji Kato
spellingShingle Ginji Omori
Kohichi Takada
Kazuyuki Murase
Naotaka Hayasaka
Hajime Nakamura
Satoshi Iyama
Hiroyuki Ohnuma
Koji Miyanishi
Fumimasa Fukuta
Toshiaki Tanaka
Naoya Masumori
Junji Kato
Successful mycophenolate mofetil treatment of a patient with severe steroid‐refractory hepatitis evoked by nivolumab plus ipilimumab treatment for relapsed bladder cancer
Clinical Case Reports
hepatitis
immune‐related adverse events
ipilimumab
mycophenolate mofetil
nivolumab
author_facet Ginji Omori
Kohichi Takada
Kazuyuki Murase
Naotaka Hayasaka
Hajime Nakamura
Satoshi Iyama
Hiroyuki Ohnuma
Koji Miyanishi
Fumimasa Fukuta
Toshiaki Tanaka
Naoya Masumori
Junji Kato
author_sort Ginji Omori
title Successful mycophenolate mofetil treatment of a patient with severe steroid‐refractory hepatitis evoked by nivolumab plus ipilimumab treatment for relapsed bladder cancer
title_short Successful mycophenolate mofetil treatment of a patient with severe steroid‐refractory hepatitis evoked by nivolumab plus ipilimumab treatment for relapsed bladder cancer
title_full Successful mycophenolate mofetil treatment of a patient with severe steroid‐refractory hepatitis evoked by nivolumab plus ipilimumab treatment for relapsed bladder cancer
title_fullStr Successful mycophenolate mofetil treatment of a patient with severe steroid‐refractory hepatitis evoked by nivolumab plus ipilimumab treatment for relapsed bladder cancer
title_full_unstemmed Successful mycophenolate mofetil treatment of a patient with severe steroid‐refractory hepatitis evoked by nivolumab plus ipilimumab treatment for relapsed bladder cancer
title_sort successful mycophenolate mofetil treatment of a patient with severe steroid‐refractory hepatitis evoked by nivolumab plus ipilimumab treatment for relapsed bladder cancer
publisher Wiley
series Clinical Case Reports
issn 2050-0904
publishDate 2021-02-01
description Abstract Mycophenolate mofetil resulted in rapid improvement of steroid‐refractory immune‐related adverse event hepatitis, induced by nivolumab plus ipilimumab.
topic hepatitis
immune‐related adverse events
ipilimumab
mycophenolate mofetil
nivolumab
url https://doi.org/10.1002/ccr3.3597
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