Development of background-free tame fluorescent probes for intracellular live cell imaging
The success of a fluorescent dye as a molecular probe to monitor the intracellular activity of biomolecules depends on its physicochemical characteristics. Here, the authors use a predictive model to identify key features that allow them to design cell permeable, background-free fluorescent probes.
Bibliographic Details
Main Authors: |
Samira Husen Alamudi,
Rudrakanta Satapathy,
Jihyo Kim,
Dongdong Su,
Haiyan Ren,
Rajkumar Das,
Lingna Hu,
Enrique Alvarado-Martínez,
Jung Yeol Lee,
Christian Hoppmann,
Eduardo Peña-Cabrera,
Hyung-Ho Ha,
Hee-Sung Park,
Lei Wang,
Young-Tae Chang |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2016-06-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/ncomms11964
|