EFFECTIVENESS OF 12-WEEK OUTPATIENT PHYSICAL REHABILITATION OF PATIENTS AFTER NON-ST-ELEVATION ACUTE CORONARY SYNDROME WITH PERCUTANEOUS CORONARY INTERVENTION ON INFARCTION-RELEVANT ARTERY

• Main Authors: К. A. Volodina, R. М. Linchak, E. Е. Achkasov, E. N. Alaeva, N. V. Tkhay, О. V. Bulgakova
• Format: Article
• Language: Russian
• Published: «SILICEA-POLIGRAF» LLC 2017-02-01
• Series: Кардиоваскулярная терапия и профилактика
• Subjects: acute coronary syndrome; exercises; rehabilitation; functional diagnostics; laboratory diagnostics
• Online Access: https://cardiovascular.elpub.ru/jour/article/view/564
• ISSN: 1728-8800; 2619-0125

Aim. To assess the efficacy of physical cardiorehabilitation in patients with acute  coronary  syndrome  non-ST-elevation  (NSTEACS)  and percutaneous coronary intervention (PCI) on infarction-relevant artery.Material  and  methods.  To  the  prospective   study,  35  patients included — mean  age  57,9±9,7  y.o.; 78% males,  22% females  after NSTEACS  with urgent  PCI on  symptom-dependent artery  and  noncomplicated  post-surgery period. Time of inclusion into the study was 2-8 weeks after ACS onset.  At 1 and 12 weeks of cardiorehabilitation programs there was functional (echocardiography, electrocardiography, exercise testing) and laboratory diagnostics  (lipids and chemistry). For 12  weeks  the  participants  visited 3  times  per  weeks  the  standard cardorehabilitation trainings.Results. After the  cardiorehabilitation  course,  in patients  we found decreae of total  cholesterol  from 4,4±1,4  to  3,9±1,1  (р=0,02);  low density lipoproteides level from 2,6±1,1 to 2,1±0,7 (р=0,002); significant increase  of high density  lipoproteides  from 0,9±0,3  to  1,2±0,4  min (р<0,001)   and  left  ventricle  ejection  fraction  from  55±8,3%  to 60,6±8,2% (p<0,001). Significant decrease of the resting heartrate (HR) from 72,9±10,3  bpm to 67,9±6 bpm (р=0,04); mean  time of the HR recovery from 4,1±1,2 min to 3,8±1 min (р=0,03) and blood pressure from 4,2±1,1 min to 3,8±1 min (р=0,013) after exercise testing; significant increase   of exercise  tolerance  to  physical  exertion  from 4,0±1,5 МЕТ to 5,0±1,7 МЕТ (p<0,001) and time of test from 5,0±1,9 min to 6,7±2 min (p<0,001).Concusion. 12-week program of cardiorehabilitation leads to significant normalization of carbohydrate  and lipid metabolisms, helps to increase exercise   tolerance   and  significantly recovers   the  hemodynamical parameters of circulation.