Quantification of [11C]PBR28 data after systemic lipopolysaccharide challenge

Quantification of [11C]PBR28 data after systemic lipopolysaccharide challenge

Abstract Background Lipopolysaccharide (LPS) is a classic immune stimulus. LPS combined with positron emission tomography (PET) 18 kDa translocator protein (TSPO) brain imaging provides a robust human laboratory model to study neuroimmune signaling. To evaluate optimal analysis of these data, this w...

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Bibliographic Details
Main Authors: Eric A. Woodcock, Martin Schain, Kelly P. Cosgrove, Ansel T. Hillmer
Format: Article
Language:English
Published: SpringerOpen 2020-03-01
Series:EJNMMI Research
Subjects:
[11C]PBR28 PET imaging
TSPO
Neuroimmune
Neuroinflammation
Lipopolysaccharide
Online Access:http://link.springer.com/article/10.1186/s13550-020-0605-7

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