Effects on prolactin secretion and binding to dopaminergic receptors in sleep-deprived lupus-prone mice

Effects on prolactin secretion and binding to dopaminergic receptors in sleep-deprived lupus-prone mice

Sleep disturbances have far-reaching effects on the neuroendocrine and immune systems and may be linked to disease manifestation. Sleep deprivation can accelerate the onset of lupus in NZB/NZWF1 mice, an animal model of severe systemic lupus erythematosus. High prolactin (PRL) concentrations are inv...

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Bibliographic Details
Main Authors: B.D. Palma, D.C. Hipolide, S. Tufik
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Systemic lupus erythematosus
NZB/NZWF1 mice
Prolactin
Stress
Autoradiography
Dopamine transporter
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000300012

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