Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons
Chronic inflammation in the substantia nigra (SN) accompanies conditions with progressive neurodegeneration. This inflammatory process contributes to gradual iron deposition that may catalyze formation of free-radical mediated damage, hence exacerbating the neurodegeneration. This study examined pro...
Main Authors: | Maj Schneider Thomsen, Michelle Vandborg Andersen, Pia Rægaard Christoffersen, Malene Duedal Jensen, Jacek Lichota, Torben Moos |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-09-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996115000856 |
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