Quinolone resistance: much more than predicted

Since quinolones are synthetic antibiotics, it was predicted that mutations in target genes would be the only mechanism through which resistance could be acquired, because there will not be quinolone resistance genes in nature. Contrary to this prediction, a variety of elements ranging from efflux p...

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Bibliographic Details
Main Authors: Alvaro eHernandez, Maria Blanca Sanchez, Jose L Martinez
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-02-01
Series:Frontiers in Microbiology
Subjects:
Qnr
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00022/full