METHODS OF OBTAINING LIPOSOMES, USED AS DRUG DELIVERY SYSTEMS (REVIEW)
The article presents an overview of the main methods for producing liposomal medications, such as convectional and acoustic methods, high pressure method, detergent dissolution and removal method and the vapor method with phase inversion. The problems of hydrophobic technology of antioxidant pharmac...
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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Series: | Разработка и регистрация лекарственных средств |
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Online Access: | https://www.pharmjournal.ru/jour/article/view/419 |
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doaj-204a122d1101425f8be49663e811e4ce2021-07-28T13:06:55ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0102134138419METHODS OF OBTAINING LIPOSOMES, USED AS DRUG DELIVERY SYSTEMS (REVIEW)A. A. Novikova0P. Kezimana1Ya. M. Stanishevskiy2Peoples' Friendship University of Russia (RUDN University) (Institute of Biochemical Technology and Nanotechnology)Peoples' Friendship University of Russia (RUDN University) (Institute of Biochemical Technology and Nanotechnology)Peoples' Friendship University of Russia (RUDN University) (Institute of Biochemical Technology and Nanotechnology)The article presents an overview of the main methods for producing liposomal medications, such as convectional and acoustic methods, high pressure method, detergent dissolution and removal method and the vapor method with phase inversion. The problems of hydrophobic technology of antioxidant pharmaceuticals (low solubility and chemical stability of such drug) and the advantages of liposomes to deliver them are reported. It is established that the most promising technology of producing liposomes containing drugs with antioxidant effects is a thin film hydration method with further sonication.https://www.pharmjournal.ru/jour/article/view/419liposomesphospholipidsdirectional transportthin film hydration methodsonication |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
A. A. Novikova P. Kezimana Ya. M. Stanishevskiy |
spellingShingle |
A. A. Novikova P. Kezimana Ya. M. Stanishevskiy METHODS OF OBTAINING LIPOSOMES, USED AS DRUG DELIVERY SYSTEMS (REVIEW) Разработка и регистрация лекарственных средств liposomes phospholipids directional transport thin film hydration method sonication |
author_facet |
A. A. Novikova P. Kezimana Ya. M. Stanishevskiy |
author_sort |
A. A. Novikova |
title |
METHODS OF OBTAINING LIPOSOMES, USED AS DRUG DELIVERY SYSTEMS (REVIEW) |
title_short |
METHODS OF OBTAINING LIPOSOMES, USED AS DRUG DELIVERY SYSTEMS (REVIEW) |
title_full |
METHODS OF OBTAINING LIPOSOMES, USED AS DRUG DELIVERY SYSTEMS (REVIEW) |
title_fullStr |
METHODS OF OBTAINING LIPOSOMES, USED AS DRUG DELIVERY SYSTEMS (REVIEW) |
title_full_unstemmed |
METHODS OF OBTAINING LIPOSOMES, USED AS DRUG DELIVERY SYSTEMS (REVIEW) |
title_sort |
methods of obtaining liposomes, used as drug delivery systems (review) |
publisher |
LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
series |
Разработка и регистрация лекарственных средств |
issn |
2305-2066 2658-5049 |
publishDate |
2019-01-01 |
description |
The article presents an overview of the main methods for producing liposomal medications, such as convectional and acoustic methods, high pressure method, detergent dissolution and removal method and the vapor method with phase inversion. The problems of hydrophobic technology of antioxidant pharmaceuticals (low solubility and chemical stability of such drug) and the advantages of liposomes to deliver them are reported. It is established that the most promising technology of producing liposomes containing drugs with antioxidant effects is a thin film hydration method with further sonication. |
topic |
liposomes phospholipids directional transport thin film hydration method sonication |
url |
https://www.pharmjournal.ru/jour/article/view/419 |
work_keys_str_mv |
AT aanovikova methodsofobtainingliposomesusedasdrugdeliverysystemsreview AT pkezimana methodsofobtainingliposomesusedasdrugdeliverysystemsreview AT yamstanishevskiy methodsofobtainingliposomesusedasdrugdeliverysystemsreview |
_version_ |
1721276826378043392 |