Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice

Heart failure (HF) and atrial fibrillation (AF) are two growing epidemics associated with significant morbidity and mortality. They often coexist due to common risk factors and shared pathophysiological mechanisms. Patients presenting with both HF and AF have a worse prognosis and present a particul...

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Main Authors: João Pedro Ferreira, Mário Santos
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/16/2/3133
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spelling doaj-20503458f96442b99b83d3f27f717a842020-11-25T00:38:34ZengMDPI AGInternational Journal of Molecular Sciences1422-00672015-01-011623133314710.3390/ijms16023133ijms16023133Heart Failure and Atrial Fibrillation: From Basic Science to Clinical PracticeJoão Pedro Ferreira0Mário Santos1Internal Medicine Department, Centro Hospitalar do Porto, Porto 4099-001, PortugalDepartment of Physiology and Cardiothoracic Surgery, Cardiovascular Research and Development Unit, Faculty of Medicine, University of Porto, Porto 4200-319, PortugalHeart failure (HF) and atrial fibrillation (AF) are two growing epidemics associated with significant morbidity and mortality. They often coexist due to common risk factors and shared pathophysiological mechanisms. Patients presenting with both HF and AF have a worse prognosis and present a particular therapeutic challenge to clinicians. This review aims to appraise the common pathophysiological background, as well as the prognostic and therapeutic implications of coexistent HF and AF.http://www.mdpi.com/1422-0067/16/2/3133atrial fibrillation (AF)heart failure (HF)pathophysiology
collection DOAJ
language English
format Article
sources DOAJ
author João Pedro Ferreira
Mário Santos
spellingShingle João Pedro Ferreira
Mário Santos
Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice
International Journal of Molecular Sciences
atrial fibrillation (AF)
heart failure (HF)
pathophysiology
author_facet João Pedro Ferreira
Mário Santos
author_sort João Pedro Ferreira
title Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice
title_short Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice
title_full Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice
title_fullStr Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice
title_full_unstemmed Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice
title_sort heart failure and atrial fibrillation: from basic science to clinical practice
publisher MDPI AG
series International Journal of Molecular Sciences
issn 1422-0067
publishDate 2015-01-01
description Heart failure (HF) and atrial fibrillation (AF) are two growing epidemics associated with significant morbidity and mortality. They often coexist due to common risk factors and shared pathophysiological mechanisms. Patients presenting with both HF and AF have a worse prognosis and present a particular therapeutic challenge to clinicians. This review aims to appraise the common pathophysiological background, as well as the prognostic and therapeutic implications of coexistent HF and AF.
topic atrial fibrillation (AF)
heart failure (HF)
pathophysiology
url http://www.mdpi.com/1422-0067/16/2/3133
work_keys_str_mv AT joaopedroferreira heartfailureandatrialfibrillationfrombasicsciencetoclinicalpractice
AT mariosantos heartfailureandatrialfibrillationfrombasicsciencetoclinicalpractice
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