Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice
Heart failure (HF) and atrial fibrillation (AF) are two growing epidemics associated with significant morbidity and mortality. They often coexist due to common risk factors and shared pathophysiological mechanisms. Patients presenting with both HF and AF have a worse prognosis and present a particul...
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doaj-20503458f96442b99b83d3f27f717a842020-11-25T00:38:34ZengMDPI AGInternational Journal of Molecular Sciences1422-00672015-01-011623133314710.3390/ijms16023133ijms16023133Heart Failure and Atrial Fibrillation: From Basic Science to Clinical PracticeJoão Pedro Ferreira0Mário Santos1Internal Medicine Department, Centro Hospitalar do Porto, Porto 4099-001, PortugalDepartment of Physiology and Cardiothoracic Surgery, Cardiovascular Research and Development Unit, Faculty of Medicine, University of Porto, Porto 4200-319, PortugalHeart failure (HF) and atrial fibrillation (AF) are two growing epidemics associated with significant morbidity and mortality. They often coexist due to common risk factors and shared pathophysiological mechanisms. Patients presenting with both HF and AF have a worse prognosis and present a particular therapeutic challenge to clinicians. This review aims to appraise the common pathophysiological background, as well as the prognostic and therapeutic implications of coexistent HF and AF.http://www.mdpi.com/1422-0067/16/2/3133atrial fibrillation (AF)heart failure (HF)pathophysiology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
João Pedro Ferreira Mário Santos |
spellingShingle |
João Pedro Ferreira Mário Santos Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice International Journal of Molecular Sciences atrial fibrillation (AF) heart failure (HF) pathophysiology |
author_facet |
João Pedro Ferreira Mário Santos |
author_sort |
João Pedro Ferreira |
title |
Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice |
title_short |
Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice |
title_full |
Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice |
title_fullStr |
Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice |
title_full_unstemmed |
Heart Failure and Atrial Fibrillation: From Basic Science to Clinical Practice |
title_sort |
heart failure and atrial fibrillation: from basic science to clinical practice |
publisher |
MDPI AG |
series |
International Journal of Molecular Sciences |
issn |
1422-0067 |
publishDate |
2015-01-01 |
description |
Heart failure (HF) and atrial fibrillation (AF) are two growing epidemics associated with significant morbidity and mortality. They often coexist due to common risk factors and shared pathophysiological mechanisms. Patients presenting with both HF and AF have a worse prognosis and present a particular therapeutic challenge to clinicians. This review aims to appraise the common pathophysiological background, as well as the prognostic and therapeutic implications of coexistent HF and AF. |
topic |
atrial fibrillation (AF) heart failure (HF) pathophysiology |
url |
http://www.mdpi.com/1422-0067/16/2/3133 |
work_keys_str_mv |
AT joaopedroferreira heartfailureandatrialfibrillationfrombasicsciencetoclinicalpractice AT mariosantos heartfailureandatrialfibrillationfrombasicsciencetoclinicalpractice |
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