Antileishmanial Activity of the Hydroalcoholic Extract of Miconia langsdorffii, Isolated Compounds, and Semi-Synthetic Derivatives

Antileishmanial Activity of the Hydroalcoholic Extract of Miconia langsdorffii, Isolated Compounds, and Semi-Synthetic Derivatives

The in vitro activity of the crude hydroalcoholic extract of the aerial parts of Miconia langsdorffii Cogn. was evaluated against the promastigote forms of L. amazonensis, the causative agent of cutaneous leishmaniasis in humans. The bioassay-guided fractionation of this extract led to identificatio...

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Main Authors: Wilson R. Cunha, Ademar A. da Silva Filho, Sérgio Albuquerque, Fransérgio F. dos Santos, Lizandra G. Magalhães, Milton Groppo, Ana H. Januário, Rodrigo Cassio Sola Veneziani, Valéria M. M. Gimenez, Juliana A. Peixoto, Antônio E. M. Crotti, Márcio Luis Andrade e Silva
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Molecules
Subjects:
antileishmanial activity
Miconia langsdorffii
oleanolic acid
ursolic acid
Online Access:http://www.mdpi.com/1420-3049/16/2/1825/

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