Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures
Increases in ocean temperature are associated with changes in the distribution of fish stocks, and the foraging regimes and maternal attendance patterns of marine mammals. However, it is not well understood how these changes affect offspring health and survival. The maternal attendance patterns and...
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doaj-20674db64d6f464690646139863a797c2021-05-05T16:16:06ZengeLife Sciences Publications LtdeLife2050-084X2018-11-01710.7554/eLife.38432Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperaturesMauricio Seguel0https://orcid.org/0000-0002-0465-236XFelipe Montalva1Diego Perez-Venegas2Josefina Gutiérrez3Hector J Paves4Ananda Müller5Carola Valencia-Soto6Elizabeth Howerth7Victoria Mendiola8Nicole Gottdenker9Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, United StatesFacultad de Ciencias Biologicas, Pontificia Universidad Catolica de Chile, Santiago, ChilePhD Program in Conservation Medicine, Facultad de Ecología y Recursos Naturales, Universidad Andrés Bello, Santiago, ChilePrograma de Investigación Aplicada en Fauna Silvestre, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile; Facultad de Ciencias Veterinarias, Instituto de Patología Animal, Universidad Austral de Chile, Valdivia, ChileDepartamento de Ciencias Básicas, Universidad Santo Tomas, Osorno, ChileInstituto de Ciencias Clínicas Veterinarias, Universidad Austral de Chile, Valdivia, ChilePrograma de Investigación Aplicada en Fauna Silvestre, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, ChileDepartment of Pathology, College of Veterinary Medicine, University of Georgia, Athens, United StatesDepartment of Pathology, College of Veterinary Medicine, University of Georgia, Athens, United StatesDepartment of Pathology, College of Veterinary Medicine, University of Georgia, Athens, United StatesIncreases in ocean temperature are associated with changes in the distribution of fish stocks, and the foraging regimes and maternal attendance patterns of marine mammals. However, it is not well understood how these changes affect offspring health and survival. The maternal attendance patterns and immunity of South American fur seals were assessed in a rookery where hookworm disease is the main cause of pup mortality. Pups receiving higher levels of maternal attendance had a positive energy balance and a more reactive immune system. These pups were able to expel hookworms through a specific immune mediated mechanism and survived the infection. Maternal attendance was higher in years with low sea surface temperature, therefore, the mean hookworm burden and mortality increased with sea surface temperature over a 10-year period. We provide a mechanistic explanation regarding how changes in ocean temperature and maternal care affect infectious diseases dynamics in a marine mammal.https://elifesciences.org/articles/38432marine mammalfur sealimmunologyclimate changeparasites |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mauricio Seguel Felipe Montalva Diego Perez-Venegas Josefina Gutiérrez Hector J Paves Ananda Müller Carola Valencia-Soto Elizabeth Howerth Victoria Mendiola Nicole Gottdenker |
spellingShingle |
Mauricio Seguel Felipe Montalva Diego Perez-Venegas Josefina Gutiérrez Hector J Paves Ananda Müller Carola Valencia-Soto Elizabeth Howerth Victoria Mendiola Nicole Gottdenker Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures eLife marine mammal fur seal immunology climate change parasites |
author_facet |
Mauricio Seguel Felipe Montalva Diego Perez-Venegas Josefina Gutiérrez Hector J Paves Ananda Müller Carola Valencia-Soto Elizabeth Howerth Victoria Mendiola Nicole Gottdenker |
author_sort |
Mauricio Seguel |
title |
Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures |
title_short |
Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures |
title_full |
Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures |
title_fullStr |
Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures |
title_full_unstemmed |
Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures |
title_sort |
immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures |
publisher |
eLife Sciences Publications Ltd |
series |
eLife |
issn |
2050-084X |
publishDate |
2018-11-01 |
description |
Increases in ocean temperature are associated with changes in the distribution of fish stocks, and the foraging regimes and maternal attendance patterns of marine mammals. However, it is not well understood how these changes affect offspring health and survival. The maternal attendance patterns and immunity of South American fur seals were assessed in a rookery where hookworm disease is the main cause of pup mortality. Pups receiving higher levels of maternal attendance had a positive energy balance and a more reactive immune system. These pups were able to expel hookworms through a specific immune mediated mechanism and survived the infection. Maternal attendance was higher in years with low sea surface temperature, therefore, the mean hookworm burden and mortality increased with sea surface temperature over a 10-year period. We provide a mechanistic explanation regarding how changes in ocean temperature and maternal care affect infectious diseases dynamics in a marine mammal. |
topic |
marine mammal fur seal immunology climate change parasites |
url |
https://elifesciences.org/articles/38432 |
work_keys_str_mv |
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