Effect of Microwave Irradiation on the Condensation of 6-Substituted 3-Formylchromones with Some Five-membered Heterocyclic Compounds
Different types of 3-substituted 4H-4-oxobenzopyrans were prepared by microwave irradiation as well as by a classical method. The beneficial effect of microwave irradiation on the aldol condensation of 3-formylchromones with 2-imino-1-methylimidazolidine-4-one (creatinine), 2-thioxoimidazolidine-4-o...
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2000-02-01
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Online Access: | http://www.mdpi.com/1420-3049/5/2/167/ |
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doaj-20977d2bca28460bbe03178e51198d232020-11-24T23:09:15ZengMDPI AGMolecules1420-30492000-02-015216717810.3390/50200167Effect of Microwave Irradiation on the Condensation of 6-Substituted 3-Formylchromones with Some Five-membered Heterocyclic CompoundsNada PronayovaTibor LiptayDusan LoosRenata GasparovaMargita LacovaDifferent types of 3-substituted 4H-4-oxobenzopyrans were prepared by microwave irradiation as well as by a classical method. The beneficial effect of microwave irradiation on the aldol condensation of 3-formylchromones with 2-imino-1-methylimidazolidine-4-one (creatinine), 2-thioxoimidazolidine-4-one (thiohydantoin) and 2-ethyl-2-thioxothiazolidin-4-one (3-ethylrhodanine) in different reaction media is described. Our results show that the effect of microwave irradiation on the reactions studied was a shortening of the reaction times and a smooth increase in the yields. The subsequent reactions of the product with some nucleophiles are discussed. The structure of the products was proven by elemental analysis, IR and NMR spectra.http://www.mdpi.com/1420-3049/5/2/167/Creatininethiohydantoinrhodaninecarbamoic acidsguanidine derivativesDiels - Alder reactionIR1H NMR13C NMR |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nada Pronayova Tibor Liptay Dusan Loos Renata Gasparova Margita Lacova |
spellingShingle |
Nada Pronayova Tibor Liptay Dusan Loos Renata Gasparova Margita Lacova Effect of Microwave Irradiation on the Condensation of 6-Substituted 3-Formylchromones with Some Five-membered Heterocyclic Compounds Molecules Creatinine thiohydantoin rhodanine carbamoic acids guanidine derivatives Diels - Alder reaction IR 1H NMR 13C NMR |
author_facet |
Nada Pronayova Tibor Liptay Dusan Loos Renata Gasparova Margita Lacova |
author_sort |
Nada Pronayova |
title |
Effect of Microwave Irradiation on the Condensation of 6-Substituted 3-Formylchromones with Some Five-membered Heterocyclic Compounds |
title_short |
Effect of Microwave Irradiation on the Condensation of 6-Substituted 3-Formylchromones with Some Five-membered Heterocyclic Compounds |
title_full |
Effect of Microwave Irradiation on the Condensation of 6-Substituted 3-Formylchromones with Some Five-membered Heterocyclic Compounds |
title_fullStr |
Effect of Microwave Irradiation on the Condensation of 6-Substituted 3-Formylchromones with Some Five-membered Heterocyclic Compounds |
title_full_unstemmed |
Effect of Microwave Irradiation on the Condensation of 6-Substituted 3-Formylchromones with Some Five-membered Heterocyclic Compounds |
title_sort |
effect of microwave irradiation on the condensation of 6-substituted 3-formylchromones with some five-membered heterocyclic compounds |
publisher |
MDPI AG |
series |
Molecules |
issn |
1420-3049 |
publishDate |
2000-02-01 |
description |
Different types of 3-substituted 4H-4-oxobenzopyrans were prepared by microwave irradiation as well as by a classical method. The beneficial effect of microwave irradiation on the aldol condensation of 3-formylchromones with 2-imino-1-methylimidazolidine-4-one (creatinine), 2-thioxoimidazolidine-4-one (thiohydantoin) and 2-ethyl-2-thioxothiazolidin-4-one (3-ethylrhodanine) in different reaction media is described. Our results show that the effect of microwave irradiation on the reactions studied was a shortening of the reaction times and a smooth increase in the yields. The subsequent reactions of the product with some nucleophiles are discussed. The structure of the products was proven by elemental analysis, IR and NMR spectra. |
topic |
Creatinine thiohydantoin rhodanine carbamoic acids guanidine derivatives Diels - Alder reaction IR 1H NMR 13C NMR |
url |
http://www.mdpi.com/1420-3049/5/2/167/ |
work_keys_str_mv |
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