Evaluation of Mesenchymal Stem Cell Therapy for Sepsis: A Randomized Controlled Porcine Study

Background: Treatment with mesenchymal stem cells (MSCs) has elicited considerable interest as an adjunctive therapy in sepsis. However, the encouraging effects of experiments with MSC in rodents have not been adequately studied in large-animal models with better relevance to human sepsis.Objectives...

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Main Authors: Jan Horak, Lukas Nalos, Vendula Martinkova, Vaclav Tegl, Lucie Vistejnova, Jitka Kuncova, Michaela Kohoutova, Dagmar Jarkovska, Martina Dolejsova, Jan Benes, Milan Stengl, Martin Matejovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00126/full