Low-frequency stimulation of the tuberomammillary nucleus facilitates electrical amygdaloid-kindling acquisition in Sprague–Dawley rats
Histamine plays a suppressive role in seizure. The tuberomammillary nucleus (TM) is the only locus of histaminergic neurons in the brain. To determine whether deep brain stimulation (DBS) of the TM provides protection against seizures, we tested the effects of low-frequency stimulation (LFS, 1 Hz),...
Main Authors: | Deng-Chang Wu, Zheng-Bing Zhu-Ge, Chao-Yang Yu, Qi Fang, Shuang Wang, Chun-Lei Jin, Shi-Hong Zhang, Zhong Chen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-10-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996108001587 |
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