Structural basis for the recognition in an idiotype-anti-idiotype antibody complex related to celiac disease.
Anti-idiotype antibodies have potential therapeutic applications in many fields, including autoimmune diseases. Herein we report the isolation and characterization of AIM2, an anti-idiotype antibody elicited in a mouse model upon expression of the celiac disease-specific autoantibody MB2.8 (directed...
Main Authors: | Anna Vangone, Safwat Abdel-Azeim, Ivana Caputo, Daniele Sblattero, Roberto Di Niro, Luigi Cavallo, Romina Oliva |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4116137?pdf=render |
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