MicroRNA-135a-5p Promotes the Functional Recovery of Spinal Cord Injury by Targeting SP1 and ROCK

MicroRNA-135a-5p Promotes the Functional Recovery of Spinal Cord Injury by Targeting SP1 and ROCK

Emerging evidence indicates that microRNAs play a pivotal role in neural remodeling after spinal cord injury (SCI). This study aimed to investigate the mechanisms of miR-135a-5p in regulating the functional recovery of SCI by impacting its target genes and downstream signaling. The gene transfection...

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Bibliographic Details
Main Authors: Nanxiang Wang, Yang Yang, Mao Pang, Cong Du, Yuyong Chen, Simin Li, Zhenming Tian, Feng Feng, Yang Wang, Zhenxiang Chen, Bin Liu, Limin Rong
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
spinal cord injury
PC12 cell
microRNA-135a-5p
SP1
ROCK
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120302651

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