Effect of positive end-expiratory pressure ventilation on central venous pressure and intraoperative blood loss in patients undergoing laparoscopic hepatectomy
Objective: Tto investigate the effects of positive end-expiratory pressure (PEEP) ventilation on central venous pressure (CVP) and intraoperative blood loss in patients undergoing laparoscopic hepatectomy. Methods: 46 cases of patients undergoing laparoscopic hepatectomy , 25 cases of male, femal...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Editorial Board of Journal of Hainan Medical University
2020-12-01
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Series: | Journal of Hainan Medical University |
Subjects: | |
Online Access: | http://www.hnykdxxb.com/PDF/202023/06.pdf |
Summary: | Objective: Tto investigate the effects of positive end-expiratory pressure (PEEP) ventilation
on central venous pressure (CVP) and intraoperative blood loss in patients undergoing
laparoscopic hepatectomy. Methods: 46 cases of patients undergoing laparoscopic
hepatectomy , 25 cases of male, female 21 cases, ASA 栺~栿 level, were randomly divided
into two groups. In group A tidal volume was set to 6 ml/kg (Predicted Body Weight, PBW)
and PEEP was set to 0 cmH2O. The tidal volume of group B was set as group A, PEEP was set
to 8 cmH2O. CVP, MAP, and Ppeak were recorded in the supine position after intubation (T0),
supine position after pneumoperitoneal (T1), anti-trendelenberg position after pneumoperitoneal
(T2), supine position after surgery (T3), and Ddyn was calculated. The amount of nitroglycerin
and the amount of blood loss were recorded. Results: Compared with group A, the CVP of
group B was significantly increased at T1 and T2 (P<0.05). Compared to T2 with T1 in group A
and group B, CVP was decreased significantly (P<0.05). At T3, Cdyn in group B was significantly
higher than that in group A (P<0.05). The amount of nitroglycerin in group B was significantly
higher than that in group A (P<0.05). There was no significant difference in intraoperative fluid
rehydration and blood loss between the two groups (P>0.05). Conclusion: PEEP with 8cmH2O
can improve Ddyn in patients undergoing laparoscopic hepatectomy, but increased CVP. It
requires more use of controlled low central venous pressure techniques to reduce intraoperative
blood loss. |
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ISSN: | 1007-1237 1007-1237 |