Medulloepithelioma: A triad of clinical features
Background: Intraocular medulloepithelioma arises from the primitive medullary epithelium and is diagnosed at a median age of five years. This tumor most commonly appears as a white, gray, or yellow-colored ciliary body tumor. The growth of medulloepithelioma is slow and it is locally invasive. Poor...
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doaj-20ed98a3468943d0a50b696b84286d002020-11-24T22:59:57ZengWolters Kluwer Medknow PublicationsOman Journal of Ophthalmology0974-620X2014-01-0172939510.4103/0974-620X.137171Medulloepithelioma: A triad of clinical featuresAni PeshtaniSwathi KalikiRalph C EagleCarol L ShieldsBackground: Intraocular medulloepithelioma arises from the primitive medullary epithelium and is diagnosed at a median age of five years. This tumor most commonly appears as a white, gray, or yellow-colored ciliary body tumor. The growth of medulloepithelioma is slow and it is locally invasive. Poor vision and pain are the most common presenting symptoms. The most common clinical signs include cyst or mass in iris, anterior chamber or ciliary body, glaucoma, and cataract. Case: A 22-month-old Caucasian female twin presented with leukocoria and poor vision in OS. Examination revealed normal findings OD and a mass in OS. Based on the clinical features of leukocoria, lens changes and a white cystic ciliary body mass in a young child, ultrasonographic, and transillumination features, the lesion was diagnosed as a non-pigmented ciliary epithelial medulloepithelioma. After enucleation, the diagnosis of malignant teratoid medulloepithelioma of the non-pigmented ciliary epithelium was confirmed. There was no evidence of tumor recurrence or systemic metastasis at three years follow-up. Conclusion: Medulloepithelioma in a child can present as a clinical triad of leukocoria, lens changes, and a white cystic ciliary body mass.http://www.ojoonline.org/article.asp?issn=0974-620X;year=2014;volume=7;issue=2;spage=93;epage=95;aulast=PeshtaniCiliary epitheliumenucleationeyemalignantmedulloepitheliomateratoidtumor |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ani Peshtani Swathi Kaliki Ralph C Eagle Carol L Shields |
spellingShingle |
Ani Peshtani Swathi Kaliki Ralph C Eagle Carol L Shields Medulloepithelioma: A triad of clinical features Oman Journal of Ophthalmology Ciliary epithelium enucleation eye malignant medulloepithelioma teratoid tumor |
author_facet |
Ani Peshtani Swathi Kaliki Ralph C Eagle Carol L Shields |
author_sort |
Ani Peshtani |
title |
Medulloepithelioma: A triad of clinical features |
title_short |
Medulloepithelioma: A triad of clinical features |
title_full |
Medulloepithelioma: A triad of clinical features |
title_fullStr |
Medulloepithelioma: A triad of clinical features |
title_full_unstemmed |
Medulloepithelioma: A triad of clinical features |
title_sort |
medulloepithelioma: a triad of clinical features |
publisher |
Wolters Kluwer Medknow Publications |
series |
Oman Journal of Ophthalmology |
issn |
0974-620X |
publishDate |
2014-01-01 |
description |
Background: Intraocular medulloepithelioma arises from the primitive medullary epithelium and is diagnosed at a median age of five years. This tumor most commonly appears as a white, gray, or yellow-colored ciliary body tumor. The growth of medulloepithelioma is slow and it is locally invasive. Poor vision and pain are the most common presenting symptoms. The most common clinical signs include cyst or mass in iris, anterior chamber or ciliary body, glaucoma, and cataract.
Case: A 22-month-old Caucasian female twin presented with leukocoria and poor vision in OS. Examination revealed normal findings OD and a mass in OS. Based on the clinical features of leukocoria, lens changes and a white cystic ciliary body mass in a young child, ultrasonographic, and transillumination features, the lesion was diagnosed as a non-pigmented ciliary epithelial medulloepithelioma. After enucleation, the diagnosis of malignant teratoid medulloepithelioma of the non-pigmented ciliary epithelium was confirmed. There was no evidence of tumor recurrence or systemic metastasis at three years follow-up.
Conclusion: Medulloepithelioma in a child can present as a clinical triad of leukocoria, lens changes, and a white cystic ciliary body mass. |
topic |
Ciliary epithelium enucleation eye malignant medulloepithelioma teratoid tumor |
url |
http://www.ojoonline.org/article.asp?issn=0974-620X;year=2014;volume=7;issue=2;spage=93;epage=95;aulast=Peshtani |
work_keys_str_mv |
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