GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma
<p>Abstract</p> <p>Background</p> <p>Allergic asthma is characterized by airway hyperresponsiveness (AHR) and allergic inflammation of the airways, driven by allergen-specific Th2 cells. The asthma phenotypes and especially AHR are sensitive to the presence and activity...
Main Authors: | Van Oosterhout Antoon JM, Van Esch Betty CAM, Gras Renée, Vissers Joost LM, Motta Alexandre C, Nawijn Martijn C |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-10-01
|
Series: | Respiratory Research |
Online Access: | http://respiratory-research.com/content/10/1/93 |
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