A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

Genetic screens are powerful tools for the functional annotation of genomes. In the context of multicellular organisms, interrogation of gene function is greatly facilitated by methods that allow spatial and temporal control of gene abrogation. Here, we describe a large-scale transgenic short guide...

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Bibliographic Details
Main Authors: Fillip Port, Claudia Strein, Mona Stricker, Benedikt Rauscher, Florian Heigwer, Jun Zhou, Celine Beyersdörffer, Jana Frei, Amy Hess, Katharina Kern, Laura Lange, Nora Langner, Roberta Malamud, Bojana Pavlović, Kristin Rädecke, Lukas Schmitt, Lukas Voos, Erica Valentini, Michael Boutros
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-02-01
Series:eLife
Subjects:
CRISPR
large-scale in vivo screens
conditional mutagenesis
genetic tools
Resource
Online Access:https://elifesciences.org/articles/53865

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