Quality of life (QOL) in patients suffering from locally advancedstage nasopharyngeal cancer before, during and after receiving carboplatin with concurrent chemoradiotherapy
Objective: To compare the quality of life (QOL) in patients suffering from locally advanced-stage nasopharyngeal cancer before, during and after treatment with carboplatin concurrent with radiation. Materials and Methods: Fifty patients diagnosed with nasopharyngeal cancer stage III or IV and who we...
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doaj-2118fb2baaf8458c987e60e0b49e4df62020-11-24T22:10:26ZengPrince of Songkla UniversityJournal of Health Science and Medical Research (JHSMR)2586-99812630-05592010-06-01283127137363Quality of life (QOL) in patients suffering from locally advancedstage nasopharyngeal cancer before, during and after receiving carboplatin with concurrent chemoradiotherapyKanyarat Chuchart0Kowit Pruegsanusak1Tanadech Dachapunkul2Patrapim Sunpaweravong3Daungji Sangthawan4Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110,Objective: To compare the quality of life (QOL) in patients suffering from locally advanced-stage nasopharyngeal cancer before, during and after treatment with carboplatin concurrent with radiation. Materials and Methods: Fifty patients diagnosed with nasopharyngeal cancer stage III or IV and who were treated with concurrent chemoradiotherapy (CCRT), were included in our study. The Thai version of the World Health Organization’s brief quality of life assessment (WHOQOLBREF- THAI), consisting of 26 indicators, was used for self-Assessment before, during and 1 month after completion of treatment. Data were analysed using Mcnema test. Results: Two-thirds of the patients were male, 44% were stage III and 56% were stage IV in nasopharyngeal cancer, respectively. The association between the physical parameters of QOL before and 1 month after treatment completion was statistically significant difference. Conclusion: Advanced-stage nasopharyngeal cancer patients, receiving carboplatin during concurrent chemoradiotherapy, exhibited a worsening especially of its physical parameters during treatment, which improved 1 month after treatment completion. The other parameters, however, remained unchanged.https://www.jhsmr.org/index.php/jhsmr/article/view/349carboplatinconcurrent chemoradiotherapynasopharyngeal cancerquality of life |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kanyarat Chuchart Kowit Pruegsanusak Tanadech Dachapunkul Patrapim Sunpaweravong Daungji Sangthawan |
spellingShingle |
Kanyarat Chuchart Kowit Pruegsanusak Tanadech Dachapunkul Patrapim Sunpaweravong Daungji Sangthawan Quality of life (QOL) in patients suffering from locally advancedstage nasopharyngeal cancer before, during and after receiving carboplatin with concurrent chemoradiotherapy Journal of Health Science and Medical Research (JHSMR) carboplatin concurrent chemoradiotherapy nasopharyngeal cancer quality of life |
author_facet |
Kanyarat Chuchart Kowit Pruegsanusak Tanadech Dachapunkul Patrapim Sunpaweravong Daungji Sangthawan |
author_sort |
Kanyarat Chuchart |
title |
Quality of life (QOL) in patients suffering from locally advancedstage nasopharyngeal cancer before, during and after receiving carboplatin with concurrent chemoradiotherapy |
title_short |
Quality of life (QOL) in patients suffering from locally advancedstage nasopharyngeal cancer before, during and after receiving carboplatin with concurrent chemoradiotherapy |
title_full |
Quality of life (QOL) in patients suffering from locally advancedstage nasopharyngeal cancer before, during and after receiving carboplatin with concurrent chemoradiotherapy |
title_fullStr |
Quality of life (QOL) in patients suffering from locally advancedstage nasopharyngeal cancer before, during and after receiving carboplatin with concurrent chemoradiotherapy |
title_full_unstemmed |
Quality of life (QOL) in patients suffering from locally advancedstage nasopharyngeal cancer before, during and after receiving carboplatin with concurrent chemoradiotherapy |
title_sort |
quality of life (qol) in patients suffering from locally advancedstage nasopharyngeal cancer before, during and after receiving carboplatin with concurrent chemoradiotherapy |
publisher |
Prince of Songkla University |
series |
Journal of Health Science and Medical Research (JHSMR) |
issn |
2586-9981 2630-0559 |
publishDate |
2010-06-01 |
description |
Objective: To compare the quality of life (QOL) in patients suffering from locally advanced-stage nasopharyngeal cancer before, during and after treatment with carboplatin concurrent with radiation.
Materials and Methods: Fifty patients diagnosed with nasopharyngeal cancer stage III or IV and who were treated with concurrent chemoradiotherapy (CCRT), were included in our study. The Thai version of the World Health Organization’s brief quality of life assessment (WHOQOLBREF- THAI), consisting of 26 indicators, was used for self-Assessment before, during and 1 month after completion of treatment. Data were analysed using Mcnema test.
Results: Two-thirds of the patients were male, 44% were stage III and 56% were stage IV in nasopharyngeal cancer, respectively. The association between the physical parameters of QOL before and 1 month after treatment completion was statistically significant difference.
Conclusion: Advanced-stage nasopharyngeal cancer patients, receiving carboplatin during concurrent chemoradiotherapy, exhibited a worsening especially of its physical parameters during treatment, which improved 1 month after treatment completion. The other parameters, however, remained unchanged. |
topic |
carboplatin concurrent chemoradiotherapy nasopharyngeal cancer quality of life |
url |
https://www.jhsmr.org/index.php/jhsmr/article/view/349 |
work_keys_str_mv |
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