Dengue encephalitis–A rare manifestation of dengue fever

• Main Authors: Deepak Madi, Basavaprabhu Achappa, John T Ramapuram, Nityananda Chowta, Mridula Laxman, Soundarya Mahalingam
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2014-05-01
• Series: Asian Pacific Journal of Tropical Biomedicine
• Subjects: Dengue encephalitis; NS1 antigen; Neurological manifestation
• Online Access: http://www.sciencedirect.com/science/article/pii/S2221169115302471

The clinical spectrum of dengue fever ranges from asymptomatic infection to dengue shock syndrome. Dengue is classically considered a non-neurotropic virus. Neurological complications are not commonly seen in dengue. The neurological manifestations seen in dengue are encephalitis, meningitis, encephalopathy, stroke and Guillain-Barré syndrome. Dengue encephalitis is a rare disease. We report an interesting case of dengue encephalitis from Southern India. A 49-year-old gentleman presented with fever, altered sensorium and seizures. Dengue NS-1 antigen test was reactive. Dengue IgM was also positive. CSF PCR was negative for herpes simplex 1 & 2. Dengue encephalitis should be considered in the differential diagnosis of fever with altered sensorium, especially in countries like India where dengue is rampant.