PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma
Abstract Background The treatment for advanced primary hepatocellular carcinoma (HCC) is sorafenib (SORA), while HCC has become increasingly drug resistant with enhanced aerobic glycolysis. The present study aimed to examine the chemotherapeutic effects of a flavonoid proanthocyanidin B2 (PB2) on HC...
Main Authors: | Jiao Feng, Liwei Wu, Jie Ji, Kan Chen, Qiang Yu, Jie Zhang, Jiaojiao Chen, Yuqing Mao, Fan Wang, Weiqi Dai, Ling Xu, Jianye Wu, Chuanyong Guo |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-05-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13046-019-1194-z |
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