Influence of NKG2D Genetic Variants on Response to Anti-TNF Agents in Patients with Rheumatoid Arthritis

Influence of NKG2D Genetic Variants on Response to Anti-TNF Agents in Patients with Rheumatoid Arthritis

A natural killer group 2 member D (NKG2D) acts as a powerful activating and co-stimulatory receptor on immune effector cells including NK and T cells. Disruptions within the NKG2D signalling pathway may trigger an exacerbated immune response and promote autoimmune reactions. The objective of the stu...

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Bibliographic Details
Main Authors:	Milena Iwaszko, Jerzy Świerkot, Katarzyna Kolossa, Sławomir Jeka, Piotr Wiland, Katarzyna Bogunia-Kubik
Format:	Article
Language:	English
Published:	MDPI AG 2018-01-01
Series:	Genes
Subjects:	NKG2D polymorphism anti-TNF therapy TNF inhibitors
Online Access:	http://www.mdpi.com/2073-4425/9/2/64

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