CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice
CD36 (fatty acid translocase) is involved in high-affinity peripheral fatty acid uptake. Mice lacking CD36 exhibit increased plasma free fatty acid and triglyceride (TG) levels and decreased glucose levels. Studies in spontaneous hypertensive rats lacking functional CD36 link CD36 to the insulin-res...
Main Authors: | Jeltje R. Goudriaan, Vivian E.H. Dahlmans, Bas Teusink, D. Margriet Ouwens, Maria Febbraio, J. Anton Maassen, Johannes A. Romijn, Louis M. Havekes, Peter J. Voshol |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2003-12-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520319441 |
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