POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION

POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION

In forensic toxicology, alternative matrices and sampling sites are required for a correlation of antemortem and postmortem concentrations with the least possible error. Postmortem redistribution phenomena and biochemical changes inherent to these processes are possible, and represent interferences...

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Main Authors: Marina Camargo Galera, Luciana Grazziotin Rossato-Grando
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2021-06-01
Series:Drug Analytical Research
Subjects:
postmortem redistribution
toxicological analyses
sampling site
vitreous humor
forensic toxicology
Online Access:https://seer.ufrgs.br/dar/article/view/111711/63353
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spelling doaj-216a0d00e28a4ffcb9a4aadaa485da072021-06-30T22:19:17ZengUniversidade Federal do Rio Grande do SulDrug Analytical Research2527-26162021-06-01511418https://doi.org/10.22456/2527-2616.111711POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATIONMarina Camargo Galera0Luciana Grazziotin Rossato-Grando1Universidade de Passo FundoUniversidade de Passo FundoIn forensic toxicology, alternative matrices and sampling sites are required for a correlation of antemortem and postmortem concentrations with the least possible error. Postmortem redistribution phenomena and biochemical changes inherent to these processes are possible, and represent interferences in these analyses. This study aimed to perform a bibliographic review through Pubmed database within a 10-year period of time, using the keywords: forensic analysis AND redistribution. We observed that for quantitative analyses the preferred matrix is blood from peripheral vessels, and when it is not available, vitreous humor is a great specimen for choice.https://seer.ufrgs.br/dar/article/view/111711/63353postmortem redistributiontoxicological analysessampling sitevitreous humorforensic toxicology
collection DOAJ
language English
format Article
sources DOAJ
author Marina Camargo Galera
Luciana Grazziotin Rossato-Grando
spellingShingle Marina Camargo Galera
Luciana Grazziotin Rossato-Grando
POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION
Drug Analytical Research
postmortem redistribution
toxicological analyses
sampling site
vitreous humor
forensic toxicology
author_facet Marina Camargo Galera
Luciana Grazziotin Rossato-Grando
author_sort Marina Camargo Galera
title POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION
title_short POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION
title_full POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION
title_fullStr POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION
title_full_unstemmed POST MORTEM CHANGES: CHALLENGES IN DRUG ANALYSIS IN THE DIAGNOSIS OF DEATHS FROM INTOXICATION
title_sort post mortem changes: challenges in drug analysis in the diagnosis of deaths from intoxication
publisher Universidade Federal do Rio Grande do Sul
series Drug Analytical Research
issn 2527-2616
publishDate 2021-06-01
description In forensic toxicology, alternative matrices and sampling sites are required for a correlation of antemortem and postmortem concentrations with the least possible error. Postmortem redistribution phenomena and biochemical changes inherent to these processes are possible, and represent interferences in these analyses. This study aimed to perform a bibliographic review through Pubmed database within a 10-year period of time, using the keywords: forensic analysis AND redistribution. We observed that for quantitative analyses the preferred matrix is blood from peripheral vessels, and when it is not available, vitreous humor is a great specimen for choice.
topic postmortem redistribution
toxicological analyses
sampling site
vitreous humor
forensic toxicology
url https://seer.ufrgs.br/dar/article/view/111711/63353
work_keys_str_mv AT marinacamargogalera postmortemchangeschallengesindruganalysisinthediagnosisofdeathsfromintoxication
AT lucianagrazziotinrossatogrando postmortemchangeschallengesindruganalysisinthediagnosisofdeathsfromintoxication
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