Moxifloxacin-warfarin interaction

Two case reports presented here show elevated prothrombin time/international normalized ratios (PT/INR) following coadministration of warfarin and moxifloxacin. Although the underlying mechanism of this interaction still remains unclear, health care providers should be careful when prescribing moxif...

Full description

Bibliographic Details
Main Authors: Yan Ji, Youssef Hokayem
Format: Article
Language:English
Published: Taylor & Francis Group 2012-01-01
Series:Journal of Community Hospital Internal Medicine Perspectives
Subjects:
Online Access:http://www.jchimp.net/index.php/jchimp/article/view/11512/pdf_1
id doaj-216f1560dde74d6ea7f86cda74aaa54f
record_format Article
spelling doaj-216f1560dde74d6ea7f86cda74aaa54f2020-11-24T23:03:45ZengTaylor & Francis GroupJournal of Community Hospital Internal Medicine Perspectives2000-96662012-01-01141310.3402/jchimp.v1i4.11512Moxifloxacin-warfarin interactionYan JiYoussef HokayemTwo case reports presented here show elevated prothrombin time/international normalized ratios (PT/INR) following coadministration of warfarin and moxifloxacin. Although the underlying mechanism of this interaction still remains unclear, health care providers should be careful when prescribing moxifloxacin to patients on warfarin therapy, especially to patients with low albumin levels. More frequent monitoring of INR in these patients may be warranted.http://www.jchimp.net/index.php/jchimp/article/view/11512/pdf_1warfarinmoxifloxacinPT/INRhypoalbuminemia
collection DOAJ
language English
format Article
sources DOAJ
author Yan Ji
Youssef Hokayem
spellingShingle Yan Ji
Youssef Hokayem
Moxifloxacin-warfarin interaction
Journal of Community Hospital Internal Medicine Perspectives
warfarin
moxifloxacin
PT/INR
hypoalbuminemia
author_facet Yan Ji
Youssef Hokayem
author_sort Yan Ji
title Moxifloxacin-warfarin interaction
title_short Moxifloxacin-warfarin interaction
title_full Moxifloxacin-warfarin interaction
title_fullStr Moxifloxacin-warfarin interaction
title_full_unstemmed Moxifloxacin-warfarin interaction
title_sort moxifloxacin-warfarin interaction
publisher Taylor & Francis Group
series Journal of Community Hospital Internal Medicine Perspectives
issn 2000-9666
publishDate 2012-01-01
description Two case reports presented here show elevated prothrombin time/international normalized ratios (PT/INR) following coadministration of warfarin and moxifloxacin. Although the underlying mechanism of this interaction still remains unclear, health care providers should be careful when prescribing moxifloxacin to patients on warfarin therapy, especially to patients with low albumin levels. More frequent monitoring of INR in these patients may be warranted.
topic warfarin
moxifloxacin
PT/INR
hypoalbuminemia
url http://www.jchimp.net/index.php/jchimp/article/view/11512/pdf_1
work_keys_str_mv AT yanji moxifloxacinwarfarininteraction
AT youssefhokayem moxifloxacinwarfarininteraction
_version_ 1725632378118864896