Identification of ADAM12 as a Novel Basigin Sheddase

Identification of ADAM12 as a Novel Basigin Sheddase

The transmembrane glycoprotein basigin, a member of the immunoglobulin superfamily, stimulates matrix metalloproteinase (MMP)-mediated extracellular matrix (ECM) degradation and thereby drives cancer cell invasion. Basigin is proteolytically shed from the cell surface and high concentrations of solu...

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Bibliographic Details
Main Authors:	Reidar Albrechtsen, Nicolai J. Wewer Albrechtsen, Sebastian Gnosa, Jeanette Schwarz, Lars Dyrskjøt, Marie Kveiborg
Format:	Article
Language:	English
Published:	MDPI AG 2019-04-01
Series:	International Journal of Molecular Sciences
Subjects:	a disintegrin and metalloproteinase EMMPRIN CD147 ectodomain shedding
Online Access:	https://www.mdpi.com/1422-0067/20/8/1957

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