The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis.
Low birth weight infant (LBWIs) are prone to mental and behavioural problems. As an important constituent of the brain and retina, long chain polyunsaturated fatty acids are essential for foetal infant mental and visual development. The effect of lactation supplemented with long chain polyunsaturate...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5892917?pdf=render |
id |
doaj-2174c81c91dc4bffb047826c484b26bc |
---|---|
record_format |
Article |
spelling |
doaj-2174c81c91dc4bffb047826c484b26bc2020-11-24T21:09:55ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01134e019566210.1371/journal.pone.0195662The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis.Yuan SongYa LiuYun PanXiaofeng YuanPengyu ChangYuan TianWeiwei CuiDong LiLow birth weight infant (LBWIs) are prone to mental and behavioural problems. As an important constituent of the brain and retina, long chain polyunsaturated fatty acids are essential for foetal infant mental and visual development. The effect of lactation supplemented with long chain polyunsaturated fatty acids (LCPUFA) on the improvement of intelligence in low birth weight children requires further validation.In this study, a comprehensive search of multiple databases was performed to identify studies focused the association between intelligence and long chain polyunsaturated fatty acid supplementation in LBWIs. Studies that compared the Bayley Scales of Infant Development (BSID) or the Wechsler Abbreviated Scale of Intelligence for Children (WISC) scores between LBWIs who were supplemented and controls that were not supplemented with LCPUFA during lactation were selected for inclusion in the meta-analysis.The main outcome was the mean difference in the mental development index (MDI) and psychomotor development index (PDI) of the BSID and the full scale intelligence quotient (FSIQ), verbal intelligence quotient (VIQ) and performance intelligence quotient (PIQ) of the WISC between LBWIs and controls. Our findings indicated that the mean BSID or WISC scores in LBWIs did not differ between the supplemented groups and controls.This meta-analysis does not reveal that LCPUFA supplementation has a significant impact on the level of intelligence in LBWIs.http://europepmc.org/articles/PMC5892917?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yuan Song Ya Liu Yun Pan Xiaofeng Yuan Pengyu Chang Yuan Tian Weiwei Cui Dong Li |
spellingShingle |
Yuan Song Ya Liu Yun Pan Xiaofeng Yuan Pengyu Chang Yuan Tian Weiwei Cui Dong Li The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis. PLoS ONE |
author_facet |
Yuan Song Ya Liu Yun Pan Xiaofeng Yuan Pengyu Chang Yuan Tian Weiwei Cui Dong Li |
author_sort |
Yuan Song |
title |
The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis. |
title_short |
The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis. |
title_full |
The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis. |
title_fullStr |
The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis. |
title_full_unstemmed |
The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis. |
title_sort |
effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: a meta-analysis. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2018-01-01 |
description |
Low birth weight infant (LBWIs) are prone to mental and behavioural problems. As an important constituent of the brain and retina, long chain polyunsaturated fatty acids are essential for foetal infant mental and visual development. The effect of lactation supplemented with long chain polyunsaturated fatty acids (LCPUFA) on the improvement of intelligence in low birth weight children requires further validation.In this study, a comprehensive search of multiple databases was performed to identify studies focused the association between intelligence and long chain polyunsaturated fatty acid supplementation in LBWIs. Studies that compared the Bayley Scales of Infant Development (BSID) or the Wechsler Abbreviated Scale of Intelligence for Children (WISC) scores between LBWIs who were supplemented and controls that were not supplemented with LCPUFA during lactation were selected for inclusion in the meta-analysis.The main outcome was the mean difference in the mental development index (MDI) and psychomotor development index (PDI) of the BSID and the full scale intelligence quotient (FSIQ), verbal intelligence quotient (VIQ) and performance intelligence quotient (PIQ) of the WISC between LBWIs and controls. Our findings indicated that the mean BSID or WISC scores in LBWIs did not differ between the supplemented groups and controls.This meta-analysis does not reveal that LCPUFA supplementation has a significant impact on the level of intelligence in LBWIs. |
url |
http://europepmc.org/articles/PMC5892917?pdf=render |
work_keys_str_mv |
AT yuansong theeffectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT yaliu theeffectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT yunpan theeffectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT xiaofengyuan theeffectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT pengyuchang theeffectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT yuantian theeffectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT weiweicui theeffectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT dongli theeffectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT yuansong effectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT yaliu effectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT yunpan effectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT xiaofengyuan effectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT pengyuchang effectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT yuantian effectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT weiweicui effectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis AT dongli effectoflongchainpolyunsaturatedfattyacidsupplementationonintelligenceinlowbirthweightinfantduringlactationametaanalysis |
_version_ |
1716757076495040512 |