ADAMTS-13 deficiency following Hemiscorpius lepturus scorpion sting
Hemiscorpius lepturus is a lethal scorpion with potentially cytotoxic venom. Various degrees of local and systemic toxicity have been observed after its envenomation ranging from local erythema to disseminated intravascular coagulation, renal failure and severe pulmonary hemorrhage. In this case rep...
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Wolters Kluwer Medknow Publications
2011-01-01
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Series: | Saudi Journal of Kidney Diseases and Transplantation |
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doaj-21a513cc9fa34764a689ecaf954c644a2020-11-24T22:15:42ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422011-01-01224792795ADAMTS-13 deficiency following Hemiscorpius lepturus scorpion stingEhsan ValaviMohammad Javad Alemzadeh AnsariSudabeh HoseiniHemiscorpius lepturus is a lethal scorpion with potentially cytotoxic venom. Various degrees of local and systemic toxicity have been observed after its envenomation ranging from local erythema to disseminated intravascular coagulation, renal failure and severe pulmonary hemorrhage. In this case report, we report on a seven-year-old patient who developed the hemolytic uremic syndrome (HUS) after being stung by the scorpion H. lepturus. This condition is characterized by microangiopathic hemolytic anemia, thrombocytopenia, increased serum levels of lactate dehydrogenase and uremia. We evaluated the causes of HUS and found that the levels of C3, C4, CH50 and H factors were normal, but the activity of Von Willebrand factor cleaving protease was decreased (less than 5% of the normal activity). The patient improved after administering therapy with plasma exchange.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=792;epage=795;aulast=Valavi |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ehsan Valavi Mohammad Javad Alemzadeh Ansari Sudabeh Hoseini |
spellingShingle |
Ehsan Valavi Mohammad Javad Alemzadeh Ansari Sudabeh Hoseini ADAMTS-13 deficiency following Hemiscorpius lepturus scorpion sting Saudi Journal of Kidney Diseases and Transplantation |
author_facet |
Ehsan Valavi Mohammad Javad Alemzadeh Ansari Sudabeh Hoseini |
author_sort |
Ehsan Valavi |
title |
ADAMTS-13 deficiency following Hemiscorpius lepturus scorpion sting |
title_short |
ADAMTS-13 deficiency following Hemiscorpius lepturus scorpion sting |
title_full |
ADAMTS-13 deficiency following Hemiscorpius lepturus scorpion sting |
title_fullStr |
ADAMTS-13 deficiency following Hemiscorpius lepturus scorpion sting |
title_full_unstemmed |
ADAMTS-13 deficiency following Hemiscorpius lepturus scorpion sting |
title_sort |
adamts-13 deficiency following hemiscorpius lepturus scorpion sting |
publisher |
Wolters Kluwer Medknow Publications |
series |
Saudi Journal of Kidney Diseases and Transplantation |
issn |
1319-2442 |
publishDate |
2011-01-01 |
description |
Hemiscorpius lepturus is a lethal scorpion with potentially cytotoxic venom. Various degrees of local and systemic toxicity have been observed after its envenomation ranging from local erythema to disseminated intravascular coagulation, renal failure and severe pulmonary hemorrhage. In this case report, we report on a seven-year-old patient who developed the hemolytic uremic syndrome (HUS) after being stung by the scorpion H. lepturus. This condition is characterized by microangiopathic hemolytic anemia, thrombocytopenia, increased serum levels of lactate dehydrogenase and uremia. We evaluated the causes of HUS and found that the levels of C3, C4, CH50 and H factors were normal, but the activity of Von Willebrand factor cleaving protease was decreased (less than 5% of the normal activity). The patient improved after administering therapy with plasma exchange. |
url |
http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=792;epage=795;aulast=Valavi |
work_keys_str_mv |
AT ehsanvalavi adamts13deficiencyfollowinghemiscorpiuslepturusscorpionsting AT mohammadjavadalemzadehansari adamts13deficiencyfollowinghemiscorpiuslepturusscorpionsting AT sudabehhoseini adamts13deficiencyfollowinghemiscorpiuslepturusscorpionsting |
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