| Summary: | Introduction: Epulis fissuratum is a tumor-like hyperplasia developing in association with an ill-fitting denture. Case Report: We report a 73-year-old female with epulis fissuratum in the soft palate as a very rare clinical location. She presented with the chief complaint of an abnormal growth along the posterior border of her ill-fitting upper complete denture as well as pain and discomfort during mastication. Intraoral examination revealed a polypoid fibrous mass, soft in consistency and smooth in texture. On history and clinical examination, a provisional diagnosis of denture-induced hyperplasia was made. The patient was prescribed topical anti-fungal medications for 10 days. Then, the lesion was excised surgically. Discussion: Histopathological examination revealed hyperplastic epithelium as well as a fibrous connective tissue with moderate inflammation which confirmed the clinical diagnosis. Although rare, epulis fissuratum can happen along the posterior portion of the upper denture and should be considered in intraoral examination.
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