HIV-1/2 indeterminate Western blot results: follow-up of asymptomatic blood donors in Belo Horizonte, Minas Gerais, Brazil
The clinical and public health importance of indeterminate results in HIV-1/2 testing is still difficult to evaluate in volunteer blood donors. At Fundação Hemominas, HIV-1/2 ELISA is used as the screening test and, if reactive, is followed by Western blot (WB). We have evaluated 84 blood donors who...
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1999-01-01
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doaj-21bd716a870f4f0f976114cf94728cd82020-11-24T23:13:27ZengUniversidade de São PauloRevista do Instituto de Medicina Tropical de São Paulo0036-46651678-99461999-01-01413155158HIV-1/2 indeterminate Western blot results: follow-up of asymptomatic blood donors in Belo Horizonte, Minas Gerais, BrazilCARNEIRO-PROIETTI A.B.F.CUNHA I.W.SOUZA M.M.OLIVEIRA D.R.MESQUITA N.M.ANDRADE C.A.CATALAN-SOARES B.C.LIMA-MARTINS M.V.C.PROIETTI F.A.The clinical and public health importance of indeterminate results in HIV-1/2 testing is still difficult to evaluate in volunteer blood donors. At Fundação Hemominas, HIV-1/2 ELISA is used as the screening test and, if reactive, is followed by Western blot (WB). We have evaluated 84 blood donors who had repeatedly reactive ELISA tests for HIV-1/2, but indeterminate WB results. Sixteen of the 84 donors (19.0%) had history of sexually transmitted diseases; 18/84 (21.4%) informed receiving or paying for sex; 3/84 (3.6%) had homosexual contact; 2/26 women (7.6%) had past history of multiple illegal abortions and 3/84 (3.6%) had been previously transfused. Four out of 62 donors (6.5%) had positive anti-nuclear factor (Hep2), with titles up to 1:640. Parasitological examination of the stool revealed eggs of S. mansoni in 4/62 (6.4%) donors and other parasites in 8/62 (12.9%). Five (5.9%) of the subjects presented overt seroconversion for HIV-1/2, 43/84 (51.2%) had negative results on the last visit, while 36/84 (42.9%) remained WB indeterminate. Although some conditions could be found associated with the HIV-1/2 indeterminate WB results and many donors had past of risky behavior, the significance of the majority of the results remains to be determined.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651999000300004HIV-1/2Indeterminate Western blotBlood donorRisk behaviors |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
CARNEIRO-PROIETTI A.B.F. CUNHA I.W. SOUZA M.M. OLIVEIRA D.R. MESQUITA N.M. ANDRADE C.A. CATALAN-SOARES B.C. LIMA-MARTINS M.V.C. PROIETTI F.A. |
spellingShingle |
CARNEIRO-PROIETTI A.B.F. CUNHA I.W. SOUZA M.M. OLIVEIRA D.R. MESQUITA N.M. ANDRADE C.A. CATALAN-SOARES B.C. LIMA-MARTINS M.V.C. PROIETTI F.A. HIV-1/2 indeterminate Western blot results: follow-up of asymptomatic blood donors in Belo Horizonte, Minas Gerais, Brazil Revista do Instituto de Medicina Tropical de São Paulo HIV-1/2 Indeterminate Western blot Blood donor Risk behaviors |
author_facet |
CARNEIRO-PROIETTI A.B.F. CUNHA I.W. SOUZA M.M. OLIVEIRA D.R. MESQUITA N.M. ANDRADE C.A. CATALAN-SOARES B.C. LIMA-MARTINS M.V.C. PROIETTI F.A. |
author_sort |
CARNEIRO-PROIETTI A.B.F. |
title |
HIV-1/2 indeterminate Western blot results: follow-up of asymptomatic blood donors in Belo Horizonte, Minas Gerais, Brazil |
title_short |
HIV-1/2 indeterminate Western blot results: follow-up of asymptomatic blood donors in Belo Horizonte, Minas Gerais, Brazil |
title_full |
HIV-1/2 indeterminate Western blot results: follow-up of asymptomatic blood donors in Belo Horizonte, Minas Gerais, Brazil |
title_fullStr |
HIV-1/2 indeterminate Western blot results: follow-up of asymptomatic blood donors in Belo Horizonte, Minas Gerais, Brazil |
title_full_unstemmed |
HIV-1/2 indeterminate Western blot results: follow-up of asymptomatic blood donors in Belo Horizonte, Minas Gerais, Brazil |
title_sort |
hiv-1/2 indeterminate western blot results: follow-up of asymptomatic blood donors in belo horizonte, minas gerais, brazil |
publisher |
Universidade de São Paulo |
series |
Revista do Instituto de Medicina Tropical de São Paulo |
issn |
0036-4665 1678-9946 |
publishDate |
1999-01-01 |
description |
The clinical and public health importance of indeterminate results in HIV-1/2 testing is still difficult to evaluate in volunteer blood donors. At Fundação Hemominas, HIV-1/2 ELISA is used as the screening test and, if reactive, is followed by Western blot (WB). We have evaluated 84 blood donors who had repeatedly reactive ELISA tests for HIV-1/2, but indeterminate WB results. Sixteen of the 84 donors (19.0%) had history of sexually transmitted diseases; 18/84 (21.4%) informed receiving or paying for sex; 3/84 (3.6%) had homosexual contact; 2/26 women (7.6%) had past history of multiple illegal abortions and 3/84 (3.6%) had been previously transfused. Four out of 62 donors (6.5%) had positive anti-nuclear factor (Hep2), with titles up to 1:640. Parasitological examination of the stool revealed eggs of S. mansoni in 4/62 (6.4%) donors and other parasites in 8/62 (12.9%). Five (5.9%) of the subjects presented overt seroconversion for HIV-1/2, 43/84 (51.2%) had negative results on the last visit, while 36/84 (42.9%) remained WB indeterminate. Although some conditions could be found associated with the HIV-1/2 indeterminate WB results and many donors had past of risky behavior, the significance of the majority of the results remains to be determined. |
topic |
HIV-1/2 Indeterminate Western blot Blood donor Risk behaviors |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651999000300004 |
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